Evidence map›Paper›PMID 18787616›Full record

ArticleInternational journal of clinical and experimental pathology2008

Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy.

Stéphane Esnault, Louis A Rosenthal, Deng-Shun Wang, James S Malter

Abstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Association between fine mapping thymic stromal lymphopoietin and atopic dermatitis onset and persistence.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Pathogenesis of atopic dermatitis: new developments.Current allergy and asthma reports · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stéphane EsnaultWaisman Center for Developmental Disabilities, the Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. sesnault@wisc.edu
Louis A Rosenthal
Deng-Shun Wang
James S Malter

Funding

Thr Role of Pin1 in AirwayP01HL088594 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI JARJOUR, NIZAR N · 2008 to 2017
$21.0M
SCOR--CELLULAR AND MOLECULAR MECHANISMS OF ASTHMAP50HL056396 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BERTICS, PAUL JOHN · 1997 to 2006
$13.8M
RV-Mediated Mechanisms of Neutrophil Motility /InflammatU19AI070503 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ROSENTHAL, LOUIS A · 2006 to 2010
$6.8M
Immunomodulatory Mechanisms of Sublingual ImmunotherapyR21AT002742 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI ROSENTHAL, LOUIS A · 2005 to 2006
$359k
Biological Significance of Oxidized NeprilysinR03AG025722 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI WANG, DENGSHUN · 2006 to 2007
$127k
NCCIH NIH HHS R21 AT002742NHLBI NIH HHS P01 HL088594NHLBI NIH HHS P50 HL056396NIAID NIH HHS U19 AI070503NIA NIH HHS R03 AG025722
6 · The paper itself

Abstract

The rising worldwide prevalence of asthma has intensified interest in the natural history of asthma. An improved understanding of the genetic, environmental, and developmental factors contributing to the inception and exacerbation of asthma will be crucial to efforts to devise effective preventive and therapeutic interventions. There is increasing evidence that the complex interplay of early life respiratory viral infections and allergic sensitization is important in the development of asthma. Major causes of asthma exacerbations are respiratory viral infections and aeroallergen exposure, which may have interactive co-morbid effects. This review describes the potential role of thymic stromal lymphopoietin (TSLP) as a connection between the innate immune response to respiratory viral infections and the type-2 adaptive immune response in the development and exacerbation of asthma.

Indexed as

asthmaatopyThymic stromal lymphopoietin (TSLP)virus infection

Identifiers

PMID18787616
PMCPMC2480547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.