Evidence map›Paper›PMID 18786916›Full record

ReviewThe Journal of biological chemistry2009

Polymethylated polysaccharides from Mycobacterium species revisited.

Mary Jackson, Patrick J Brennan

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  8. Distribution of glucan-branching enzymes among prokaryotes.Cellular and molecular life sciences : CMLS · 2016
    Review
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mary JacksonDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, USA.
Patrick J Brennan
Colorado State University · US

Funding

Biogenesis of Lipoarabinomannan in MycobacteriaR01AI064798 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI JACKSON, MARY · 2005 to 2019
$5.4M
NIAID NIH HHS AI064798NIAID NIH HHS R01 AI064798
6 · The paper itself

Abstract

Mycobacteria produce two sets of unusual polymethylated polysaccharides, the 3-O-methylmannose polysaccharides and the 6-O-methylglucose lipopolysaccharides. Both polysaccharides localize to the cytoplasm, where they have been postulated to regulate fatty acid metabolism due to their ability to form stable 1:1 complexes with fatty acyl chains. Physiological evidence for this assumption is lacking, however. Recent advances in our knowledge of the processes underlying sugar transfer in mycobacteria, together with the availability of genome sequences and tools for the genetic manipulation of these microorganisms, have opened the way to the elucidation of the biosynthetic pathways and biological functions of these unique carbohydrates.

Indexed as

Bacterial ProteinsMethylationModels, MolecularMycobacteriumPolysaccharidesBacterial ProteinsPolysaccharides

Identifiers

PMID18786916
PMCPMC2629103
OpenAlexW1994448362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.