Evidence map›Paper›PMID 18786811›Full record

ArticleSchizophrenia research2009

Bridging the gap between schizophrenia and psychotic mood disorders: Relating neurocognitive deficits to psychopathology.

Matthew J Smith, Deanna M Barch, John G Csernansky

Abstract read
In one paragraph

Article in Schizophrenia research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  6. Cognitive impairments in psychotic disorders: common mechanisms and measurement.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Matthew J SmithDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA. matthewsmith@northwestern.edu
Deanna M Barch
John G Csernansky
Northwestern University · USWashington University in St. Louis · US

Funding

STRUCTURE, FUNCTION AND COGNITION IN SCHIZOPHRENIAP50MH071616 · NIMH · WASHINGTON UNIVERSITY · PI CHEVERUD, JAMES M · 2004 to 2008
$11.2M
NEUROMORPHOMETRY IN SCHIZOPHRENIA BY COMPUTER ALGORITHMR01MH056584 · NIMH · WASHINGTON UNIVERSITY · PI CSERNANSKY, JOHN G · 1998 to 2011
$4.2M
PSYCHIATRIC EPIDEMIOLOGY &BIOSTATISTICST32MH017104 · NIMH · WASHINGTON UNIVERSITY · PI COTTLER, LINDA B · 1985 to 2007
$2.5M
NIMH NIH HHS P50 MH071616NIMH NIH HHS R01 MH056584NIMH NIH HHS T32 MH017104
6 · The paper itself

Abstract

backgroundThe neurobiological relationship between schizophrenia and psychotic mood disorders is not well understood. Neurocognitive deficits have been described in both types of disorders and have been proposed to reflect underlying neurobiological dysfunction. Examining the relationship between neurocognitive function and psychopathology could help illuminate the neurobiological relationship between schizophrenia and psychotic mood disorders.

methodsParticipants included 72 individuals with DSM-IV schizophrenia, 25 individuals with schizoaffective disorder or bipolar disorder with psychotic features, and 72 community controls. Standardized scores and correlations between four domains of neurocognition and psychopathology were examined.

resultsIndividuals with schizophrenia and psychotic mood disorders scored similarly on several dimensions of neurocognitive function and psychopathology. The relationships between neurocognitive function and psychopathology were similar in the two groups.

conclusionsIndividuals with schizophrenia and psychotic mood disorders were similar in terms of both the level of impairment in neurocognitive function and psychopathology, as well as in the relationship between the two dimensions of illness. These results suggest that schizophrenia and psychotic mood disorders such as schizoaffective disorder and bipolar disorder with psychotic features are on a neurobiological continuum.

Indexed as

Cognition DisordersAdultBrainDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleNeuropsychological TestsPsychotic DisordersSchizophreniaSchizophrenic PsychologySeverity of Illness Index

Identifiers

PMID18786811
PMCPMC2647814
OpenAlexW2110722785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.