Evidence map›Paper›PMID 18786382›Full record

ReviewCurrent biology : CB2008

Timing in cellular Ca2+ signaling.

Michael J Boulware, Jonathan S Marchant

Open access · bronzeAbstract readReview
In one paragraph

Review in Current biology : CB, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 65 citations in OpenAlex.

  1. With or without a CaPlanta · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Light-Induced Nanoscale Deformation in Azobenzene Thin Film Triggers Rapid Intracellular CaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. CaJournal of cellular physiology · 2021
    Article
  14. Article
  15. CaCold Spring Harbor perspectives in biology · 2019
    Review
  16. Review
  17. STIM1 Knockout Enhances PDGF-Mediated CaInternational journal of molecular sciences · 2018
    Article
  18. Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a CaBiochimica et biophysica acta. Molecular cell research · 2017
    Article
  19. Single-cell resolution of intracellular T cell CaIntegrative biology : quantitative biosciences from nano to macro · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael J BoulwareDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.
Jonathan S Marchant
University of Minnesota Medical Center · US

Funding

Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7M
Functional architecture of IP3-evoked local Ca2+signalsR01NS046783 · NINDS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MARCHANT, JONATHAN S · 2004 to 2007
$819k
NIGMS NIH HHS R01 GM088790NINDS NIH HHS NS046783NINDS NIH HHS R01 NS046783
6 · The paper itself

Abstract

Calcium (Ca2+) signals are generated across a broad time range. Kinetic considerations impact how information is processed to encode and decode Ca2+ signals, the choreography of responses that ensure specific and efficient signaling and the overall temporal amplification such that ephemeral Ca2+ signals have lasting physiological value. The reciprocal importance of timing for Ca2+ signaling, and Ca2+ signaling for timing is exemplified by the altered kinetic profiles of Ca2+ signals in certain diseases and the likely role of basal Ca2+ fluctuations in the perception of time itself.

Indexed as

CalciumCalcium SignalingFeedback, PhysiologicalKineticsModels, BiologicalTime FactorsCalcium

Identifiers

PMID18786382
PMCPMC3236564
OpenAlexW2062864424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.