ArticleNeuron2008
A time and a place for nkx2-1 in interneuron specification and migration.
Article in Neuron, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Multimodal classification of neurons in the lateral septum.bioRxiv : the preprint server for biology · 2026Article
- A distinct lineage pathway drives parvalbumin chandelier cell fate in human interneuron reprogramming.Science advances · 2026Article
- Cortical versus hippocampal network dysfunction in a human brain assembloid model of epilepsy and intellectual disability.Cell reports · 2025Article
- Experience-Dependent Intrinsic Plasticity in Layer IV of Barrel Cortex at Whisking Onset.eNeuro · 2025Article
- Immediately following the onset of active whisking, the input layer of barrel cortex exhibits a transient period of increased excitability that depends on prior experience.bioRxiv : the preprint server for biology · 2025Article
- An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression.Nature communications · 2022Article
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- Neuronal tangential migration from Nkx2.1-positive hypothalamus.Brain structure & function · 2020Article
- The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.Nature communications · 2020Article
- Article
- Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung's disease.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2018Article
- The effects of short-term high-fat feeding on exercise capacity: multi-tissue transcriptome changes by RNA sequencing analysis.Lipids in health and disease · 2017Article
- Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells.PloS one · 2017Article
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- Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.Neuron · 2014Article
- A developmental and genetic classification for malformations of cortical development: update 2012.Brain : a journal of neurology · 2012Review
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Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The homeobox transcription factor, Nkx2-1, plays multiple roles during forebrain development. Using restricted genetic ablation of Nkx2-1, in this issue of Neuron, Butt et al. show that Nkx2-1 in telencephalic progenitors regulates interneuron subtype specification, while Nóbrega-Pereira et al. demonstrate that postmitotic Nkx2-1 regulates migration and sorting of interneurons to the striatum or cortex by controlling the expression of the guidance receptor, Neuropilin-2.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.