ReviewHistology and histopathology2008
Ets transcription factors in intestinal morphogenesis, homeostasis and disease.
Review in Histology and histopathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 48 citations in OpenAlex.
- Review
- Exosomes Derived From miR-212-5p Overexpressed Human Synovial Mesenchymal Stem Cells Suppress Chondrocyte Degeneration and Inflammation by Targeting ELF3.Frontiers in bioengineering and biotechnology · 2022Article
- Elf3 deficiency during zebrafish development alters extracellular matrix organization and disrupts tissue morphogenesis.PloS one · 2022Article
- ANANSE: an enhancer network-based computational approach for predicting key transcription factors in cell fate determination.Nucleic acids research · 2021Article
- Large intestine embryogenesis: Molecular pathways and related disorders (Review).International journal of molecular medicine · 2020Review
- Genetic variants associated with alcohol dependence co-ordinate regulation of ADH genes in gastrointestinal and adipose tissues.Scientific reports · 2020Article
- Article
- The prognosis analysis ofTranslational cancer research · 2020Article
- LncGata6-controlled stemness in regeneration and cancer.Non-coding RNA investigation · 2019Article
- Elevated expression of p53 in early colon polyps in a pig model of human familial adenomatous polyposis.Journal of applied genetics · 2018Article
- MK2 and ETV1 Are Prognostic Factors in Esophageal Adenocarcinomas.Journal of Cancer · 2018Article
- Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks.Genome medicine · 2017Article
- Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.PLoS biology · 2017Article
- Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer.World journal of gastroenterology · 2014Review
- Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Role of tight junctions in signal transduction: an update.EXCLI journal · 2014Review
- Control of MicroRNA-21 expression in colorectal cancer cells by oncogenic epidermal growth factor/Ras signaling and Ets transcription factors.DNA and cell biology · 2012Article
- The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells.Nature immunology · 2012Article
- Article
- RNA-Seq quantification of the human small airway epithelium transcriptome.BMC genomics · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Ets transcription factors comprise a large family of sequence-specific regulators of gene expression with important and diverse roles in development and disease. Most Ets family members are expressed in the developing and/or mature intestine, frequently in a compartment-specific and temporally dynamic manner. However, with the exception of the highly expressed Elf3, involved in embryonic epithelial differentiation, little is known about Ets functions in intestinal development and homeostasis. Ets factors show altered expression in colon cancer, where they regulate pathways relevant to tumor progression. Ets factors also likely act as important modifiers of non-neoplastic intestinal disease by regulating pathways relevant to tissue injury and repair. Despite a large body of published work on Ets biology, much remains to be learned about the precise functions of this large and diverse gene family in intestinal morphogenesis, homeostasis, and both neoplastic and non-neoplastic pathology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.