Evidence map›Paper›PMID 18784939›Full record

ReviewPflugers Archiv : European journal of physiology2009

Ca(2+) signaling by T-type Ca(2+) channels in neurons.

Lucius Cueni, Marco Canepari, John P Adelman, Anita Lüthi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Activity-Dependent Calcium Signaling in Neurons of the Medial Superior Olive during Late Postnatal Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Journal of advanced research · 2016
    Article
  9. Article
  10. Review
  11. Combining Membrane Potential Imaging with Other Optical Techniques.Advances in experimental medicine and biology · 2015
    Review
  12. Article
  13. Article
  14. T-type channels buddy up.Pflugers Archiv : European journal of physiology · 2014
    Review
  15. Role for T-type Ca2+ channels in sleep waves.Pflugers Archiv : European journal of physiology · 2014
    Review
  16. T-type channel-mediated neurotransmitter release.Pflugers Archiv : European journal of physiology · 2014
    Review
  17. Role of T-type channels in vasomotor function: team player or chameleon?Pflugers Archiv : European journal of physiology · 2014
    Review
  18. Article
  19. Review
  20. Synaptic plasticity at intrathalamic connections via CaV3.3 T-type Ca2+ channels and GluN2B-containing NMDA receptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucius CueniBiozentrum, University of Basel, Switzerland.
Marco Canepari
John P Adelman
Anita Lüthi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the major families of voltage-gated Ca(2+) channels, the low-voltage-activated channels formed by the Ca(v)3 subunits, referred to as T-type Ca(2+) channels, have recently gained increased interest in terms of the intracellular Ca(2+) signals generated upon their activation. Here, we provide an overview of recent reports documenting that T-type Ca(2+) channels act as an important Ca(2+) source in a wide range of neuronal cell types. The work is focused on T-type Ca(2+) channels in neurons, but refers to non-neuronal cells in cases where exemplary functions for Ca(2+) entering through T-type Ca(2+) channels have been described. Notably, Ca(2+) influx through T-type Ca(2+) channels is the predominant Ca(2+) source in several neuronal cell types and carries out specific signaling roles. We also emphasize that Ca(2+) signaling through T-type Ca(2+) channels occurs often in select subcellular compartments, is mediated through strategically co-localized targets, and is exploited for unique physiological functions.

Indexed as

AnimalsCalciumCalcium Channels, T-TypeCalcium SignalingExocytosisIon Channel GatingNeuronal PlasticityNeuronsSmall-Conductance Calcium-Activated Potassium ChannelsCalciumCalcium Channels, T-TypeSmall-Conductance Calcium-Activated Potassium Channels

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.