ArticleJournal of human hypertension2009
Reasons for therapeutic inertia when managing hypertension in clinical practice in non-Western countries.
Article in Journal of human hypertension, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical inertia in the pharmacological management of hypertension: A systematic review and meta-analysis.Medicine · 2018Pooled it
- The concept and definition of therapeutic inertia in hypertension in primary care: a qualitative systematic review.BMC family practice · 2014Pooled it
- Association of Low-Dose Triple Combination Therapy With Therapeutic Inertia and Prescribing Patterns in Patients With Hypertension: A Secondary Analysis of the TRIUMPH Trial.JAMA cardiology · 2020Trial
- Trial
- [Prevention of therapeutic inertia in the treatment of arterial hypertension by using a program of home blood pressure monitoring].Atencion primaria · 2012Trial
- Is there a predictive profile for clinical inertia in hypertensive patients? An observational, cross-sectional, multicentre study.Drugs & aging · 2011Trial
- Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications.The EPMA journal · 2025Article
- Simplified Approach to Managing Newly Diagnosed Patients with Mild-to-Moderate Hypertension in Routine Clinical Practice.Advances in therapy · 2025Observational
- Therapeutic inertia and contributing factors among ambulatory patients with hypertension.BMC cardiovascular disorders · 2024Observational
- Article
- Management of Hypertension in the Asia-Pacific Region: A Structured Review.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024Review
- A Cross-Sectional Survey of Fixed-Dose Combination Antihypertensive Medicine Prescribing in Twenty-Four Countries, Including Qualitative Insights.Global heart · 2024Article
- Uncontrolled blood pressure and therapeutic inertia in treated hypertensive patients: A retrospective cohort study using a UK general practice database.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Home Blood Pressure Control and Drug Prescription Patterns among Thai Hypertensives: A 1-Year Analysis of Telehealth Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project.International journal of hypertension · 2021Article
- [São Paulo call to action for the prevention and control of high blood pressure: 2020Llamado a la acción de San Pablo para la prevención y el control de la hipertensión arterial, 2020].Revista panamericana de salud publica = Pan American journal of public health · 2021Article
- [São Paulo call to action for the prevention and control of high blood pressure: 2020Chamado à ação de São Paulo para prevenção e controle da hipertensão arterial: 2020].Revista panamericana de salud publica = Pan American journal of public health · 2021Article
- Longitudinal control of blood pressure among a cohort of Ghanaians with hypertension: A multicenter, hospital-based study.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Hypertension control in sub-Saharan Africa: Clinical inertia is another elephant in the room.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- São Paulo call to action for the prevention and control of high blood pressure: 2020.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Polypills for primary prevention of cardiovascular disease.Nature reviews. Cardiology · 2019Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insufficient awareness of hypertension guidelines by physicians may be an impediment to achieving adequate blood pressure (BP) control rates in clinical practice. We therefore conducted an open intervention survey among primary care physicians in 1596 centres from 16 countries in four different continents to prospectively assess what is the BP goal defined by physicians for individual patients and what are the reasons for not intensifying antihypertensive treatment when BP goals are not achieved. Enrolled patients (N=35,302) were either not treated to goal (N=22,887) or previously untreated (N=12,250). Baseline systolic and diastolic BP averaged 159/95+/-15/12 mm Hg. BP goals defined by physicians averaged 136+/-6 mm Hg for systolic and 86+/-5 mm Hg for diastolic BP. Patients' individual risk stratification determined BP goals. At last visit BP averaged 132/81+/-11/8 mm Hg and values of <or=140/90 were reached in 92% of untreated and 80% of previously uncontrolled treated hypertensives. The main reasons for not intensifying antihypertensive treatment when BP remained above goal were the assumption that the time after starting the new drug was too short to attain its full effect, the satisfaction with a clear improvement of BP or with a BP nearing the goal, and the acceptance of good self-measurements. In this open intervention program in primary care, a large proportion of patients achieved recommended BP goals. The belief that a clear improvement in BP is acceptable and that the full drug effect may take up to several weeks to be reached are frequent reasons for treatment inertia when goals are not achieved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.