ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2008
Spatiotemporal profiles of field potentials in mouse superior colliculus analyzed by multichannel recording.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Neuronal Features of Visual Attention in the Mouse Superior Colliculus Depend on Learned Behavioral Relevance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Measuring spatial visual loss in rats by retinotopic mapping of the superior colliculus using a novel multi-electrode array technique.Journal of neuroscience methods · 2024Article
- Sensorimotor transformation elicits systematic patterns of activity along the dorsoventral extent of the superior colliculus in the macaque monkey.Communications biology · 2019Article
- The Mouse Superior Colliculus: An Emerging Model for Studying Circuit Formation and Function.Frontiers in neural circuits · 2018Review
- Reduced Frequency of Ipsilateral Express Saccades in Cervical Dystonia: Probing the Nigro-Tectal Pathway.Tremor and other hyperkinetic movements (New York, N.Y.) · 2018Article
- Segregation of Visual Response Properties in the Mouse Superior Colliculus and Their Modulation during Locomotion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Linear distributed source modeling of local field potentials recorded with intra-cortical electrode arrays.PloS one · 2017Article
- Expanding neurochemical investigations with multi-modal recording: simultaneous fast-scan cyclic voltammetry, iontophoresis, and patch clamp measurements.The Analyst · 2016Article
- Effects of a pretarget distractor on saccade reaction times across space and time in monkeys and humans.Journal of vision · 2016Article
- Linking express saccade occurance to stimulus properties and sensorimotor integration in the superior colliculus.Journal of neurophysiology · 2015Article
- Optogenetic investigation of the role of the superior colliculus in orienting movements.Behavioural brain research · 2013Article
- Optimal control of saccades by spatial-temporal activity patterns in the monkey superior colliculus.PLoS computational biology · 2012Article
- Inverse current source density method in two dimensions: inferring neural activation from multielectrode recordings.Neuroinformatics · 2011Article
- Circuit dynamics of the superior colliculus revealed by in vitro voltage imaging.Annals of the New York Academy of Sciences · 2011Article
- Intralaminar and interlaminar activity within the rodent superior colliculus visualized with voltage imaging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Exploring the superior colliculus in vitro.Journal of neurophysiology · 2009Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The onset and vector of orienting behaviors, such as saccades, are controlled by commands that descend from a population of neurons in deep layers of the superior colliculus (dSC). In this study, to characterize the role of the collicular local circuitry that generates the spatiotemporal pattern of command activity in the dSC neuronal population, responses evoked by single-pulse electrical stimulation in superficial layers of the superior colliculus (sSC) were analyzed by a 64-channel field potential recording system (planar electrode, 8 x 8 pattern; 150 microm interelectrode spacing) in slices obtained from 16- to 22-d-old mice. A negative field potential with short latency and short duration spatially restricted to the recording sites in sSC was evoked adjacent to the stimulation site. After bath application of 10 mum bicuculline, the same stimulus induced a large negative field response with long duration that spread from sSC to dSC. The dSC potential initially showed a positive response, presumably because of reversal of the negative potential that originated in sSC, and then a long negative response that spread horizontally as far as 1 mm. These responses disappeared after application of an NMDA receptor antagonist, 2-amino-5-phosphonovelarate, indicating that NMDA receptors have an important role in the generation of these responses. Simultaneous whole-cell patch-clamp recordings showed that the long-lasting negative field potentials corresponded to the depolarization accompanying burst spike activity of SC neurons. The present study revealed an extensive excitatory network in the dSC that may contribute to the generation of activity by a large population of neurons that discharge before a saccade.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.