ArticleJournal of neurophysiology2008
Top-down regulation of plasticity in the birdsong system: "premotor" activity in the nucleus HVC predicts song variability better than it predicts song features.
Article in Journal of neurophysiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- A Microclip Peripheral Nerve Interface (μcPNI) for Bioelectronic Interfacing with Small Nerves.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Manipulations of inhibition in cortical circuitry differentially affect spectral and temporal features of Bengalese finch song.Journal of neurophysiology · 2020Article
- Evidence for a causal inverse model in an avian cortico-basal ganglia circuit.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Rhythmic cortical neurons increase their oscillations and sculpt basal ganglia signaling during motor learning.Developmental neurobiology · 2013Article
- Vocal exploration is locally regulated during song learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Changes in the neural control of a complex motor sequence during learning.Journal of neurophysiology · 2011Article
- Deafening-induced vocal deterioration in adult songbirds is reversed by disrupting a basal ganglia-forebrain circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Song practice promotes acute vocal variability at a key stage of sensorimotor learning.PloS one · 2010Article
- Modulation of perineuronal nets and parvalbumin with developmental song learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Daily and developmental modulation of "premotor" activity in the birdsong system.Developmental neurobiology · 2009Article
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Authors and funding
4 authors.
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Abstract
We studied real-time changes in brain activity during active vocal learning in the zebra finch songbird. The song nucleus HVC is required for the production of learned song. To quantify the relationship of HVC activity and behavior, HVC population activity during repeated vocal sequences (motifs) was recorded and temporally aligned relative to the motif, millisecond by millisecond. Somewhat surprisingly, HVC activity did not reliably predict any vocal feature except amplitude and, to a lesser extent, entropy and pitch goodness (sound periodicity). Variance in "premotor" HVC activity did not reliably predict variance in behavior. In contrast, HVC activity inversely predicted the variance of amplitude, entropy, frequency, pitch, and FM. We reasoned that, if HVC was involved in song learning, the relationship of HVC activity to learned features would be developmentally regulated. To test this hypothesis, we compared the HVC song feature relationships in adults and juveniles in the sensorimotor "babbling" period. We found that the relationship of HVC activity to variance in FM was developmentally regulated, with the greatest difference at an HVC vocalization lag of 50 ms. Collectively, these data show that, millisecond by millisecond, bursts in HVC activity predict song stability on-line during singing, whereas decrements in HVC activity predict plasticity. These relationships between neural activity and plasticity may play a role in vocal learning in songbirds by enabling the selective stabilization of parts of the song that match a learned tutor model.
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