ArticleMalaria journal2008
Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing.
Article in Malaria journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.
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Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Global prevalence and mortality of severe Plasmodium malariae infection: a systematic review and meta-analysis.Malaria journal · 2020Pooled it
- Malaria epidemiological research in the Republic of Congo.Malaria journal · 2016Pooled it
- Unveiling the overlooked burden of malaria misdiagnosis using lamp-based re-evaluation of routine malaria diagnosis in health centers: implications for public health and clinical practice in Northwest Ethiopia.BMC infectious diseases · 2026Article
- Prevalence of non-Plasmodium falciparum species in southern districts of Brazzaville in The Republic of the Congo.Parasites & vectors · 2022Article
- The primate malaria parasites Plasmodium malariae, Plasmodium brasilianum and Plasmodium ovale spp.: genomic insights into distribution, dispersal and host transitions.Malaria journal · 2022Review
- Nationwide molecular surveillance of three Plasmodium species harboured by symptomatic malaria patients living in Ghana.Parasites & vectors · 2022Article
- Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates.Malaria journal · 2021Article
- The epidemiology of Plasmodium vivax among adults in the Democratic Republic of the Congo.Nature communications · 2021Article
- Under the Radar: Epidemiology of Plasmodium ovale in the Democratic Republic of the Congo.The Journal of infectious diseases · 2021Article
- High frequency of the Duffy-negative genotype and absence of Plasmodium vivax infections in Ghana.Malaria journal · 2021Article
- Clinical Sequelae Associated with Unresolved Tropical Splenomegaly in a Cohort of Recently Resettled Congolese Refugees in the United States-Multiple States, 2015-2018.The American journal of tropical medicine and hygiene · 2020Article
- The enigmatic mechanisms by which Plasmodium vivax infects Duffy-negative individuals.PLoS pathogens · 2020Review
- Article
- Unexpected high circulation of Plasmodium vivax in asymptomatic children from Kédougou, southeastern Senegal.Malaria journal · 2017Article
- The Molecular Basis of Erythrocyte Invasion by Malaria Parasites.Cell host & microbe · 2017Review
- Antibodies elicited during natural infection in a predominantly Plasmodium falciparum transmission area cross-react with sexual stage-specific antigen in P. vivax.Acta tropica · 2017Article
- Wild African great apes as natural hosts of malaria parasites: current knowledge and research perspectives.Primate biology · 2017Review
- Key Knowledge Gaps for Plasmodium vivax Control and Elimination.The American journal of tropical medicine and hygiene · 2016Article
- Widespread distribution of Plasmodium vivax malaria in Mauritania on the interface of the Maghreb and West Africa.Malaria journal · 2016Article
- The role of folate in malaria - implications for home fortification programmes among children aged 6-59 months.Maternal & child nutrition · 2015Review
Corrections and comments
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Authors and funding
17 authors at 10 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlasmodium vivax is estimated to affect 75 million people annually. It is reportedly absent, however, from west and central Africa due to the high prevalence of the Duffy negative phenotype in the indigenous populations. Despite this, non-African travellers consistently return to their own countries with P. vivax malaria after visiting this region. An attempt was made, therefore, to detect the presence of P. vivax parasites in blood samples collected from the indigenous populations of west and central Africa.
methodsParasite species typing (for all four human malaria parasites) was carried out by PCR on 2,588 blood samples collected from individuals from nine African malaria-endemic countries.
resultsMost infections (98.5%) were Plasmodium falciparum, Plasmodium malariae was identified in 8.5% of all infections, and Plasmodium ovale in 3.9%. The prevalence of both parasites varied greatly by country. Only one case of P. vivax was detected from Sao Tome, an island off the west coast of Africa, confirming the scarcity of this parasite in Africa.
conclusionThe prevalence of P. vivax in local populations in sub-Saharan Africa is very low, despite the frequent identification of this parasite in non-African travellers.
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