ArticleScandinavian journal of immunology2008
Beginning of the end of (understanding) the immune response.
Article in Scandinavian journal of immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Immune-neuroendocrine reactivity and features of tuberculosis in pregnancy.Frontiers in medicine · 2025Review
- Role and Function of Regulatory T Cell in Chronic Rhinosinusitis with Nasal Polyposis.Journal of immunology research · 2022Review
- Diet Associated with Inflammation and Alzheimer's Disease.Journal of Alzheimer's disease reports · 2019Review
- Treg Heterogeneity, Function, and Homeostasis.Frontiers in immunology · 2019Review
- Helicobacter pylori neutrophil-activating protein: a potential Treg modulator suppressing allergic asthma?Frontiers in microbiology · 2015Article
- Co-inhibitory molecules: Controlling the effectors or controlling the controllers?Self/nonself · 2010Article
- How do regulatory T cells work?Scandinavian journal of immunology · 2009Review
- On the critique by Colin Anderson of 'A reply to Dembic: on an end to the beginning of mis-understanding the immune response'.Scandinavian journal of immunology · 2009Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The algorithm about the workings of the immune system should incorporate in its basic form the ability to explain several basic features: the ability to reject pathogens, to respond differently to invasions by class switching, to retain memory of rejecting past infections, the regulatory T-cell formation and the acquisition of a life-long antigen tolerance in adults. The Danger and the two self-non-self theories - Pathogenicity (Janeway) and the Associated Antigen Recognition (Langman and Cohn) - cannot explain satisfactorily one or more of these issues. By failing to find appropriate solutions to help their corresponding basic algorithms to be operative, these theories negate, instead of finding explanations (no matter how complicated) for interpretations of certain results, one of them being the existence of a regulatory cell as a physiological component of the immune system. On the other hand, the integrity model can incorporate regulatory T cells in a basic algorithm of the workings of the immune system, explaining it as a downregulation of the immune response provided advantageous commensalism prevails over disadvantages of parasitism.
Indexed as
Identifiers
18782266What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.