Evidence map›Paper›PMID 18782265›Full record

ArticleScandinavian journal of immunology2008

A rationalized set of default postulates that permit a coherent description of the immune system amenable to computer modeling.

M Cohn

Abstract read
In one paragraph

Article in Scandinavian journal of immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Immune System as a Sensory System.International journal of biomedical science : IJBS · 2010
    Article
  3. The evolutionary context for a self-nonself discrimination.Cellular and molecular life sciences : CMLS · 2010
    Article
  4. Bridging innate and adaptive antitumor immunity targeting glycans.Journal of biomedicine & biotechnology · 2010
    Review
  5. How do regulatory T cells work?Scandinavian journal of immunology · 2009
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

M CohnConceptual Immunology Group, The Salk Institute for Biological Studies, La Jolla, CA, USA. cohn@salk.edu

Funding

EVOLUTIONARY MODELS OF THE IMMUNE SYSTEMR01RR007716 · NCRR · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI COHN, MELVIN · 1991 to 2010
$4.5M
NCRR NIH HHS R01 RR007716NCRR NIH HHS RR07716
6 · The paper itself

Abstract

This discussion delineates and rationalizes a set of postulates that permit a coherent understanding of immune function. Although analytical tools such as mathematics and computer modeling have become very popular, simulation and data mining in the absence of a conceptual framework cannot increase understanding. The goal of this essay is to provide the foundation for a discussion that has as its goal the formulation of an agreed upon set of default postulates. Such a set is required to guide the algorithms needed to analyze complex immune behavior.

Indexed as

Computer SimulationModels, ImmunologicalAlgorithmsAnimalsComputational BiologyHumansImmune System

Identifiers

PMID18782265
PMCPMC2581492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.