ArticleBritish journal of clinical pharmacology2008
Shift of statin use towards the elderly in 1995-2005: a nation-wide register study in Finland.
Article in British journal of clinical pharmacology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Incidence in pharmacoepidemiology: A conceptual framework for incidence of a single substance or group of substances with statins as an example.Basic & clinical pharmacology & toxicology · 2023Article
- Characterising complex health needs and the use of preventive therapies in the older population: a population-based cohort analysis of UK primary care and hospital linked data.BMC geriatrics · 2023Article
- Eleven-Year Trends in Lipid-Modifying Medicines Utilisation and Expenditure in a Low-Income Country: A Study from the Republic of Srpska, Bosnia and Herzegovina.ClinicoEconomics and outcomes research : CEOR · 2023Article
- LDL-cholesterol trajectories and statin treatment in Finnish type 2 diabetes patients: a growth mixture model.Scientific reports · 2021Article
- Prevalence and Incidence of Statin Use and 3-Year Adherence and Discontinuation Rates Among Older Adults With Dementia.American journal of Alzheimer's disease and other dementias · 2018Article
- Role of Helicobacter pylori and interleukin 6 -174 gene polymorphism in dyslipidemia: a case-control study.BMJ open · 2016Article
- Effect of statin use on outcome of symptomatic cholelithiasis: a case-control study.BMC gastroenterology · 2014Article
- Trends in statin therapy initiation during the period 2000-2010 in Israel.European journal of clinical pharmacology · 2014Article
- Monitoring the use of lipid-lowering medication among persons with newly diagnosed diabetes: a nationwide register-based study.BMJ open · 2013Article
- Statin use among older Finns stratified according to cardiovascular risk.European journal of clinical pharmacology · 2013Article
- Suboptimal use of statins at treatment initiation.European journal of clinical pharmacology · 2011Article
- Review
- No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.British journal of clinical pharmacology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo describe nation-wide secular trends in statin use.
methodsReimbursed prescriptions for lipid lowering drugs between 1995 and 2005 in Finland were retrieved from the nation-wide Prescription Register. The 1 year prevalence and incidence of statin use stratified by gender and age of users were measured for each calendar year. The relative changes (RR) in the incidence and the prevalence were calculated by using the year 1995 as a reference.
resultsThe 1 year prevalence increased 11-fold (95% confidence interval 11.2, 11.5), i.e. from 7.8 per 1000 inhabitants in 1995 to 88.9 in 2005. The incidence increased five-fold (95% CI 4.9, 5.1) from 355 per 100 000 inhabitants to 1772 during the respective years. The prevalence and incidence were the highest among persons aged 65-74 years. The largest relative increase in incidence was found among those aged >/= 75 years, in both females (RR 14.1, 95% CI 13.0, 15.3) and males (RR 14.0, 95% CI 12.5, 15.7). Since 2002 the prevalence has been higher among females (P < 0.05).
conclusionsAs statin use has increased particularly among the elderly, further studies on the benefits in real life situation are needed in this age group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.