ArticleMycopathologia2009
Frequency of Candida spp. in the oral cavity of Brazilian HIV-positive patients and correlation with CD4 cell counts and viral load.
Article in Mycopathologia, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Raman Spectroscopy of OralInternational journal of molecular sciences · 2022Article
- Antifungal Drug Susceptibility ofFrontiers in microbiology · 2017Article
- Sensitivity of clinical isolates of Candida to essential oils from Burseraceae family.EXCLI journal · 2016Article
- Spectrum and the In Vitro Antifungal Susceptibility Pattern of Yeast Isolates in Ethiopian HIV Patients with Oropharyngeal Candidiasis.International journal of microbiology · 2016Article
- Evaluation of gene expression SAP5, LIP9, and PLB2 of Candida albicans biofilms after photodynamic inactivation.Lasers in medical science · 2015Article
- Systemic Staphylococcus aureus infection mediated by Candida albicans hyphal invasion of mucosal tissue.Microbiology (Reading, England) · 2015Article
- Asymptomatic oral yeast carriage and antifungal susceptibility profile of HIV-infected patients in Kunming, Yunnan Province of China.BMC infectious diseases · 2013Article
- Microbiologic profile of endodontic infections from HIV- and HIV+ patients using multiple-displacement amplification and checkerboard DNA-DNA hybridization.Oral diseases · 2012Article
- Opportunistic microorganisms in patients undergoing antibiotic therapy for pulmonary tuberculosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2011Article
- Pathogenesis and treatment of oral candidosis.Journal of oral microbiology · 2011Article
- Distribution and antifungal susceptibility profile of oropharyngealTherapeutic advances in infectious diseaseArticle
- Association of oral candidal species with human immunodeficiency virus patients of West Godavari district, Andhra Pradesh - AnJournal of oral and maxillofacial pathology : JOMFPArticle
- Presence of Candida spp. in the oral cavity of heart transplantation patients.Journal of applied oral science : revista FOBArticle
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8 authors.
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Abstract
The aim of this study was to evaluate the prevalence of Candida spp., and particularly C. dubliniensis, among oral isolates from Brazilian HIV-positive patients correlating these results with CD4 cell counts and viral load. Forty-five individuals (23 female and 22 male) diagnosed as HIV-positive by ELISA and Western-blot, under anti-retroviral therapy for at least 1 year and without oral candidosis signals were included in the study. The control group was constituted by 45 healthy individuals, matched to the test group in relation to age, gender, and oral conditions. Oral rinses were collected and the identification was performed by phenotypic tests. The existence of C. dubliniensis among the isolates was analyzed using a validated multiplex PCR assay. Candida spp. were detected at significantly higher number in the oral cavity of HIV-positive patients in relation to the controls (P = 0.0008). C. albicans was the most frequently isolated species in both groups. In the HIV group, C. glabrata, C. lipolytica, C. krusei, C. guilliermondii, and C. parapsilosis were also identified. In the control group, we additionally identified C. tropicalis and C. dubliniensis. Two isolates (1.9%, 2/108) from control individuals were identified as C. dubliniensis and this species was not verified in the HIV group. Candida spp. counts were statistically lower (P = 0.0230) in the oral cavity of patients with low viral load (<400 copies/mm(3)). Candida spp. counts did not differ statistically among groups with different levels of CD4 cells counts (P = 0.1068).
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