Evidence map›Paper›PMID 18780228›Full record

ReviewJournal of neurovirology2008

Opiates, immune system, acquired immunodeficiency syndrome, and nonhuman primate model.

Richard J Noel, Vanessa Rivera-Amill, Shilpa Buch, Anil Kumar

Abstract readReview
In one paragraph

Review in Journal of neurovirology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  2. Review
  3. Opioid-Mediated HIV-1 Immunopathogenesis.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.The Journal of pharmacology and experimental therapeutics · 2016
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Translational research in NeuroAIDS: a neuroimmune pharmacology-related course.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2011
    Article
  14. Update on animal models for HIV research.European journal of immunology · 2009
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Richard J NoelPonce School of Medicine, Ponce, Puerto Rico.
Vanessa Rivera-Amill
Shilpa Buch
Anil Kumar
Ponce Health Sciences University · PRUniversity Medical Center · USUniversity of Missouri–Kansas City · US

Funding

Efffects of opiate virus/host response in SHIV/macaqueR01DA015013 · NIDA · UNIVERSITY OF MISSOURI KANSAS CITY · PI KUMAR, ANIL · 2001 to 2011
$3.1M
NIDA NIH HHS DA015013NIDA NIH HHS R01 DA015013
6 · The paper itself

Abstract

Both human immunodeficiency virus (HIV) and illicit drug addiction remain major health problems not only in the United States but all over globe. The effect of drug addiction on HIV/AIDS (acquired immunodeficiency syndrome) has been somewhat underexplored. However, in United States more than one fourth of HIV-positive individuals are injection drug users. Opiates are known to negatively affect the immune system, and therefore may have deleterious effects on progression of disease among HIV-infected individuals. This review discusses the effects of opiates on immune system as well as its effect on HIV replication and AIDS progression. In addition, the effects of opiates on disease progression in non-human primate model of AIDS is presented with at least one possible reason for rapid disease progression in multi-virus the challenge model.

Indexed as

NarcoticsAcquired Immunodeficiency SyndromeAnimalsDisease Models, AnimalDisease ProgressionImmune SystemOpioid-Related DisordersPrimatesNarcotics

Identifiers

PMID18780228
PMCPMC4086310
OpenAlexW2139052215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.