Evidence map›Paper›PMID 18779440›Full record

ReviewHypertension (Dallas, Tex. : 1979)2008

Modulation of the endocannabinoid system in cardiovascular disease: therapeutic potential and limitations.

Pál Pacher, Partha Mukhopadhyay, Rajesh Mohanraj, Grzegorz Godlewski, Sándor Bátkai, George Kunos

Open access · greenAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. Antagonist-elicited cannabis withdrawal in humans.Journal of clinical psychopharmacology · 2011
    Trial
  3. Article
  4. Chemical Probes for Investigating the Endocannabinoid System.Current topics in behavioral neurosciences · 2026
    Review
  5. Review
  6. Cannabinoids in preclinical research of sepsis: a scoping review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  7. Article
  8. Review
  9. Cannabinoids: Role in Neurological Diseases and Psychiatric Disorders.International journal of molecular sciences · 2024
    Review
  10. Cardiovascular (side) effects of cannabis.Wiener klinische Wochenschrift · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pál PacherSection on Oxidative Stress Tissue Injury, Laboratory of Physiological Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892-9413, USA. pacher@mail.nih.gov
Partha Mukhopadhyay
Rajesh Mohanraj
Grzegorz Godlewski
Sándor Bátkai
George Kunos
National Institute on Alcohol Abuse and Alcoholism · US

Funding

Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injuryZIAAA000375 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI PACHER, PAL · 2009 to 2025
$27.8M
Endocannabinoids And The Control Of Cardiovascular FunctionZIAAA000351 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI KUNOS, GEORGE · 2009 to 2025
$11.8M
Endocannabinoids And The Control Of Vascular ToneZ01AA000351 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI KUNOS, GEORGE · 2001 to 2008
$1.8M
Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injuryZ01AA000375 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI PACHER, PAL · 2006 to 2008
$1.3M
Intramural NIH HHS Z01 AA000375Intramural NIH HHS Z99 AA999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EndocannabinoidsCannabinoid Receptor ModulatorsCannabinoidsCardiovascular DiseasesCentral Nervous System AgentsHumansTreatment OutcomeCannabinoid Receptor ModulatorsCannabinoidsCentral Nervous System AgentsEndocannabinoids

Identifiers

PMID18779440
PMCPMC2568884
OpenAlexW2106049697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.