ArticleInfant behavior & development2008
Developmental changes in the responses of preterm infants to a painful stressor.
Article in Infant behavior & development, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Methodological Issues in the Study of the Development of Pain Responsivity in Preterm Neonates: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Development of Cardiovascular Indices of Acute Pain Responding in Infants: A Systematic Review.Pain research & management · 2016Pooled it
- Understanding infant stress in neonatal and pediatric intensive care: a scoping review.Intensive care medicine. Paediatric and neonatal · 2025Review
- The influence of gestational age in the psychometric testing of the Bernese Pain Scale for Neonates.BMC pediatrics · 2019Article
- Nociceptive Cortical Activity Is Dissociated from Nociceptive Behavior in Newborn Human Infants under Stress.Current biology : CB · 2017Article
- Individual contextual factors in the validation of the Bernese pain scale for neonates: protocol for a prospective observational study.BMC pediatrics · 2017Observational
- Controversies in preterm brain injury.Neurobiology of disease · 2016Review
- Examining the side effects of sucrose for pain relief in preterm infants: a case-control study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014Article
- Gentle Human Touch and Yakson: The Effect on Preterm's Behavioral Reactions.ISRN nursing · 2012Article
- Assessing pain in preterm infants in the neonatal intensive care unit: moving to a 'brain-oriented' approach.Pain management · 2011Article
- Measures of Stress Exposure for Hospitalized Preterm Infants.Nursing researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
The purpose of this investigation was to examine longitudinally gestational age and developmental differences in preterm infants' self-regulatory abilities in response to a painful stressor, as well as associations between behavioral and cardiovascular responses. Participants included 49 healthy premature infants. Behavioral and cardiovascular responses to a heel stick blood draw were compared between infants of 28-31 and 32-34 weeks' gestation age at birth. Both gestational age groups displayed behavioral and cardiovascular indications of stress in response to the blood draw. However, both shortly after birth and several weeks later, infants born at younger gestational ages (28-31 weeks) were more physiologically reactive. Evidence that the behavioral stress responses of 28-31 weeks' gestation age group preterm infants do not reflect their physiological responses suggests that evaluation of preterm infants' experiences and risk require assessments of both physiology and behavior. The greater stress vulnerability of the 28-31 weeks' gestation group relative to the 32-34 weeks' gestation group and the implications of this for subsequent development are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.