Evidence map›Paper›PMID 18775371›Full record

ReviewChild and adolescent psychiatric clinics of North America2008

Complementary and alternative medicine treatments for children with autism spectrum disorders.

Susan E Levy, Susan L Hyman

2 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Child and adolescent psychiatric clinics of North America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01676389 nacompletednot on this mapstarted 2013, after this paper: background citation

Osteopathic Manual Medicine Treatment in Autism, A Pilot Study

TypeinterventionalSponsorNew York Institute of TechnologyRan2013 to 2015Enrolled3ConditionsAutism Spectrum DisordersArmsSham OMM, Osteopathic Manual Medicine (Body Therapy)
NCT05340049 nacompletednot on this mapstarted 2021, after this paper: background citation

Early Craniosacral Therapy Improves Infant Neurodevelopment in Apparently Healthy Children.

TypeinterventionalSponsorClinica Gema LeonRan2021 to 2022Enrolled120ConditionsChild Development DisorderArmsAcademic behavioral intervention of teachers, Therapy sessions
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 206 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Public Perception of Autism Treatments: The Role of Credibility and Evidence.Journal of autism and developmental disorders · 2019
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Complementary and Alternative Therapies for Autism Spectrum Disorder.Evidence-based complementary and alternative medicine : eCAM · 2015
    Review
  17. Intervention for optimal outcome in children and adolescents with a history of autism.Journal of developmental and behavioral pediatrics : JDBP · 2014
    Article
  18. Advanced pharmacotherapy evidenced by pathogenesis of autism spectrum disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2014
    Review
  19. Eating habits and dietary patterns in children with autism.Eating and weight disorders : EWD · 2014
    Article
  20. The role of nutraceuticals in the management of autism.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Susan E LevyDepartment of Pediatrics, University of Pennsylvania School of Medicine, The Children's Hospital of Philadelphia, 3405 Civic Center Boulevard, Philadelphia, PA 19104, USA. levys@email.chop.edu
Susan L Hyman
Golisano Children's Hospital · USUniversity of Pennsylvania · US

Funding

UNIVERSITY OF ROCHESTER'S RESEARCH ASSOCIATE ORGANIZATIONUL1RR024160 · NCRR · UNIVERSITY OF ROCHESTER · PI PEARSON, THOMAS ARTHUR · 2006 to 2011
$38.7M
YOHIMBINE CHALLENGE IN PARKINSONIAN PATIENTS WITH PANIC DISORDERM01RR000044 · NCRR · UNIVERSITY OF ROCHESTER · PI GUZICK, DAVID S · 1985 to 2006
$13.8M
GENOTYPE AND PHENOTYPE OF BRAINSTEM INJURY IN AUTISMP01HD035466 · NICHD · UNIVERSITY OF ROCHESTER · PI RODIER, PATRICIA M · 1998 to 2002
$2.8M
NCRR NIH HHS M01 RR000044NCRR NIH HHS UL1 RR024160NCRR NIH HHS UL1RR024160NICHD NIH HHS P01 HD035466NICHD NIH HHS P01HD35466
6 · The paper itself

Abstract

Complementary and alternative medical (CAM) treatments are commonly used for children with autism spectrum disorders. This review discusses the evidence supporting the most frequently used treatments, including categories of mind-body medicine, energy medicine, and biologically based, manipulative, and body-based practices, with the latter two treatments the most commonly selected by families. Clinical providers need to understand the evidence for efficacy (or lack thereof) and potential side effects. Some CAM practices have evidence to reject their use, such as secretin, whereas others have emerging evidence to support their use, such as melatonin. Most treatments have not been adequately studied and do not have evidence to support their use.

Indexed as

Complementary TherapiesAdolescentAutistic DisorderChildCombined Modality TherapyDietary SupplementsEvidence-Based MedicineHumansRandomized Controlled Trials as Topic

Identifiers

PMID18775371
PMCPMC2597185
OpenAlexW2039424378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.