ArticleCurrent hypertension reports2008
Does earlier attainment of blood pressure goal translate into fewer cardiovascular events?
Article in Current hypertension reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Systolic Blood Pressure Response in SPRINT (Systolic Blood Pressure Intervention Trial) and ACCORD (Action to Control Cardiovascular Risk in Diabetes): A Possible Explanation for Discordant Trial Results.Journal of the American Heart Association · 2017Trial
- Total antihypertensive therapeutic intensity score and its relationship to blood pressure reduction.Journal of the American Society of Hypertension : JASH · 2016Trial
- Is there a predictive profile for clinical inertia in hypertensive patients? An observational, cross-sectional, multicentre study.Drugs & aging · 2011Trial
- Efficacy and safety of initial combination therapy with amlodipine/valsartan compared with amlodipine monotherapy in black patients with stage 2 hypertension: the EX-STAND study.Journal of human hypertension · 2009Trial
- Screening and Treatment for Subclinical Hypertensive Heart Disease in Emergency Department Patients With Uncontrolled Blood Pressure: A Cost-effectiveness Analysis.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2017Article
- No Time to Waste: in Support of Aggressive and Immediate Management of Hypertension.Current hypertension reports · 2016Review
- Recognition and Management of Hypertension in Older Persons: Focus on African Americans.Journal of the American Geriatrics Society · 2015Review
- Current perspectives on combination therapy in the management of hypertension.Integrated blood pressure control · 2013Article
- The relationship of ethnicity to the prevalence and management of hypertension and associated chronic kidney disease.BMC nephrology · 2011Article
- Role of triple fixed combination valsartan, amlodipine and hydrochlorothiazide in controlling blood pressure.Patient preference and adherence · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Recently, clinical trial data showed that rapid attainment of goal blood pressure (BP) reduces the risk for cardiovascular disease (CVD) events. It is unknown whether patient characteristics linked to the magnitude of CVD risk influence the speed of BP control. Time to attain goal systolic BP (SBP) in Kaplan-Meier survival curves was contrasted for strata of baseline characteristics and intensity of hypertension treatment. Survival analyses showed that albuminuria, diabetes, increased body mass index, millimeters of mercury above Joint National Committee (JNC) SBP goal, higher Framingham risk score, older age, depressed estimated glomerular filtration rate, and greater intensity of antihypertensive drug treatment all predicted slower JNC SBP goal attainment (P < 0.015); the intensity of antihypertensive drug therapy when goal BP was attained was also greater in all conditions linked to slow goal attainment. Cox proportional hazards model that included the above patient characteristics revealed all characteristics slowed attainment of JNC SBP goals (P < 0.03). Thus, patient characteristics influence speed of BP control and practitioners should avoid therapeutic inertia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.