ReviewImmunologic research2008
Translational applications of antibody phage display.
Review in Immunologic research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Proteomic Analysis of Pemphigus Autoantibodies Indicates a Larger, More Diverse, and More Dynamic Repertoire than Determined by B Cell Genetics.Cell reports · 2017Article
- Immunogenicity of therapeutic recombinant immunotoxins.Immunological reviews · 2016Review
- Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library.BMC biotechnology · 2012Article
- Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis.PloS one · 2012Article
- Generation of recombinant guinea pig antibody fragments to the human GABAC receptor.Journal of immunological methods · 2011Article
- Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/TEM1, using a paired yeast-display/secretory scFv library platform.Journal of immunological methods · 2011Article
- Review
- Systems approaches to design of targeted therapeutic delivery.Wiley interdisciplinary reviews. Systems biology and medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Recent developments in molecular immunology have facilitated the expression of immune repertoires in the form of immunoglobulin fragments on the surface of filamentous bacteriophage. Such approaches, known as "phage display", have provided powerful tools for producing monoclonal antibodies for research, clinical, and therapeutic applications. Our laboratory has combined these techniques with novel selection methods to isolate extraordinarily large arrays of human antibodies that can be used for developing new diagnostic reagents and methods for their use, as well as reagents that may serve as leads for the design of novel therapeutic molecules. In particular, application of phage display to the study of antibody-mediated autoimmune disease, notably idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, and pemphigus have facilitated comprehensive genetic and serologic analyses of pathogenic autoantibodies thereby offering new insights into disease pathophysiology and approaches for their treatment.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.