ReviewNature reviews. Cancer2008
Can genes for mammographic density inform cancer aetiology?
Review in Nature reviews. Cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01160510 (Genetics of Mammographic Appearances and Patterns), which is not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Genetics of Mammographic Appearances and Patterns (The GenMap Study)
Who cites it
28 citing papers in PubMed, 41 citations in OpenAlex.
- Hormone replacement therapy dependent changes in breast cancer-related gene expression in breast tissue of healthy postmenopausal women.Molecular oncology · 2011Trial
- Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone.Signal transduction and targeted therapy · 2022Article
- Mammographic breast density and IGF-1 gene polymorphisms rs1520220, rs2946834 and rs6219 in Polish women.Contemporary oncology (Poznan, Poland) · 2021Article
- Single nucleotide polymorphisms of insulin-like growth factor gene and mammographic breast density.Przeglad menopauzalny = Menopause review · 2020Article
- Alcohol intake from early adulthood to midlife and mammographic density.Cancer causes & control : CCC · 2016Article
- Article
- Associations between breast density and a panel of single nucleotide polymorphisms linked to breast cancer risk: a cohort study with digital mammography.BMC cancer · 2015Article
- Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer.PloS one · 2014Article
- New genetic variants improve personalized breast cancer diagnosis.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2014Article
- Emerging Concepts in Breast Cancer Risk Prediction.Current obstetrics and gynecology reports · 2013Article
- Genetic variants improve breast cancer risk prediction on mammograms.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013Article
- Integrative cancer epidemiology--the next generation.Cancer discovery · 2012Article
- Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users.Breast cancer research : BCR · 2012Article
- Estrogen metabolism and mammographic density in postmenopausal women: a cross-sectional study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2012Article
- Mammographic breast density and breast cancer: evidence of a shared genetic basis.Cancer research · 2012Article
- No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density.Breast cancer research : BCR · 2012Article
- Clinical and epidemiological issues in mammographic density.Nature reviews. Clinical oncology · 2011Review
- Article
- Altered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial content.Molecular endocrinology (Baltimore, Md.) · 2011Article
- Breast tissue composition and susceptibility to breast cancer.Journal of the National Cancer Institute · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Mammographic density (MD) reflects variations in fat, stromal and epithelial tissues that are thought to be regulated by several genes. High MD is an established risk factor for breast cancer; therefore, genes that regulate MD may indirectly influence breast cancer. These genes might also be fewer in number and easier to identify than those for breast cancer risk outside of inherited predisposition syndromes. In this Perspective, we review the limited genetic studies of MD and propose future directions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.