Evidence map›Paper›PMID 18772429›Full record

ArticleScience (New York, N.Y.)2008

Shadow enhancers as a source of evolutionary novelty.

Joung-Woo Hong, David A Hendrix, Michael S Levine

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 323 papers.

0numbers the graph read from it
0cells of the map it votes in
323citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

323 citing papers in PubMed.

  1. Article
  2. Synthetic Regulatory Genomics.Annual review of genomics and human genetics · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Evolution of repressive sequences within an enhancer contributed to morphological diversity in crucifer plants.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Regulatory logic of neuronal identity specification inbioRxiv : the preprint server for biology · 2025
    Article
  18. Article
  19. Article
  20. Review

263 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Joung-Woo HongDepartment of Molecular and Cell Biology, Division of Genetics, Genomics, and Development, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA.
David A Hendrix
Michael S Levine

Funding

MOLECULAR CHARACTERIZATION OF THE DORSAL MORPHOGENR37GM046638 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LEVINE, MICHAEL STEVEN · 2003 to 2012
$3.8M
MOLECULAR CHARACTERIZATION OF THE DORSAL MORPHOGENR01GM046638 · NIGMS · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI LEVINE, MICHAEL STEVEN · 1991 to 2016
$2.3M
NIGMS NIH HHS GM46638NIGMS NIH HHS R01 GM046638
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Enhancer Elements, GeneticEvolution, MolecularAnimalsBinding SitesBody PatterningChromatin ImmunoprecipitationComputational BiologyDrosophilaDrosophila melanogasterDrosophila ProteinsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalIntronsNuclear ProteinsOligonucleotide Array Sequence AnalysisPhosphoproteinsdl protein, DrosophilaDrosophila ProteinsNuclear ProteinsPhosphoproteinsTranscription Factors

Identifiers

PMID18772429
PMCPMC4257485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.