ReviewMicrobiology and molecular biology reviews : MMBR2008
Cross-species virus transmission and the emergence of new epidemic diseases.
Review in Microbiology and molecular biology reviews : MMBR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 443 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
443 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of loneliness and social isolation scales used in epidemics and pandemics.Psychiatry research · 2021Pooled it
- Beyond H5N1: influenza A virus infection in bovine udder organoids.Emerging microbes & infections · 2026Article
- Article
- Disulfide bonds stabilize the SARS-CoV-2 RBD and preserve binding to ACE2 following thermal denaturation.Bioscience reports · 2026Article
- Pangolin-Associated Viruses: Diversity, Evolutionary Adaptation, and Zoonotic Spillover Risks.Animals : an open access journal from MDPI · 2026Review
- RNA Virus Diversity, Cross-Species Transmission, and Molecular Constraints in Two Closely Related Rat Species.Integrative zoology · 2026Article
- Immunoinformatics-Guided Computational Design and In Silico Validation of Multi-Epitope Vaccine Candidates Targeting Canine and Feline Parvoviruses.Microorganisms · 2026Article
- Assessing the Origin of the COVID19 Pandemic Is Still Important.FASEB bioAdvances · 2026Article
- Standing HA phenotypic breadth shapes H5N1 cross-host potential.Research square · 2026Article
- Emerging Viral Zoonoses: Epidemiology, Vaccination Strategies, and Implications for Global Public Health.Vaccines · 2026Review
- Combined generalist and host-specific transcriptional strategies enable host generalism in the fungal pathogenProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Distinct evolutionary patterns of endemic and emerging parvoviruses and the origin of a new pandemic virus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Animal organoids as transformative platforms for viral infections and zoonotic cross-species viral research.Journal of virology · 2026Review
- Temporal Dynamics and Turnover of Rabbit Hemorrhagic Disease Virus 2 (RHDV2/GI.2) in Wild Lagomorphs from Northeastern Spain.Microbial ecology · 2026Article
- Impact of high-order time-delayed information on epidemic propagation in multiplex networks.Infectious Disease Modelling · 2026Article
- Pathogen host jump risk is not predicted by spillover rate, but rather by novelty.PLoS biology · 2026Article
- Viral surveillance of invasive mammals in New Zealand reveals unique viral lineages reflecting their introduction history.Journal of virology · 2026Article
- Gammaretrovirus Infections in Humans in the Past, Present, and Future: Have We Defeated the Pathogen?Pathogens (Basel, Switzerland) · 2026Review
- Highly divergent virome in wild rodents of Xinjiang, China: Implications for rodent origin of porcine reproductive and respiratory syndrome virus 1.Zoological research · 2026Article
- Zoon0PredV: Potential Virus Species Crossover Prediction Using Convolutional Neural Networks and Viral Protein Sequence Patterns.Bioinformatics and biology insights · 2026Article
383 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Host range is a viral property reflecting natural hosts that are infected either as part of a principal transmission cycle or, less commonly, as "spillover" infections into alternative hosts. Rarely, viruses gain the ability to spread efficiently within a new host that was not previously exposed or susceptible. These transfers involve either increased exposure or the acquisition of variations that allow them to overcome barriers to infection of the new hosts. In these cases, devastating outbreaks can result. Steps involved in transfers of viruses to new hosts include contact between the virus and the host, infection of an initial individual leading to amplification and an outbreak, and the generation within the original or new host of viral variants that have the ability to spread efficiently between individuals in populations of the new host. Here we review what is known about host switching leading to viral emergence from known examples, considering the evolutionary mechanisms, virus-host interactions, host range barriers to infection, and processes that allow efficient host-to-host transmission in the new host population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.