ArticlePediatric nephrology (Berlin, Germany)2009
Membranous nephritis associated with acquired cytomegalovirus infection in a 19-month-old baby.
Article in Pediatric nephrology (Berlin, Germany), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Virus-Associated Nephropathies: A Narrative Review.International journal of molecular sciences · 2022Review
- Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation - an experimental study.Transplant international : official journal of the European Society for Organ Transplantation · 2018Article
- Clinicopathological features of atypical membranous nephropathy with unknown etiology in adult Chinese patients.Medicine · 2018Article
- Viruses and collapsing glomerulopathy: a brief critical review.Clinical kidney journal · 2013Review
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Membranous nephritis (MN) is a rare form of glomerulonephritis in childhood, with an incidence of 0.8 to 6.7% based on renal biopsy specimens. Although the disease is considered to be idiopathic in the majority of cases, especially in adults, MN has been associated with various infectious agents, such as hepatitis Beta virus. The natural history of MN in childhood remains unknown because of its rarity, and to the best of our knowledge, no case of MN linked to cytomegalovirus (CMV) infection in an immunocompetent child has been described to date. We report here a 19-month-old female infant who presented with a maculopapular rash, fever, and nephritic-nephrotic syndrome. Virology tests for infectious diseases revealed a recent CMV infection. The renal biopsy findings were compatible with MN, while PCR analysis of the renal tissue specimen was positive for CMV DNA. Antiviral treatment (ganciclovir) resulted in full remission of proteinuria and hematuria. Two years after the initial diagnosis, the child remains well and asymptomatic without clinical or laboratory evidence of the disease.
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