Trial reportJournal of perinatology : official journal of the California Perinatal Association2009
Enhanced kangaroo mother care for heel lance in preterm neonates: a crossover trial.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02434432 (Music Therapy as a Method of Non-Pharmacological Pain Management in the NICU Setting), which is not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Music Therapy as a Method of Non-Pharmacological Pain Management in the NICU Setting
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Musical and vocal interventions to improve neurodevelopmental outcomes for preterm infants.The Cochrane database of systematic reviews · 2023Pooled it
- Non-pharmacological management of infant and young child procedural pain.The Cochrane database of systematic reviews · 2023Pooled it
- Skin-to-skin care for procedural pain in neonates.The Cochrane database of systematic reviews · 2017Pooled it
- Non-pharmacological management of infant and young child procedural pain.The Cochrane database of systematic reviews · 2015Pooled it
- The Effect of Breastfeeding Versus Sensorial Saturation on Infants' Behavioral Responses of Pain following Pentavalent Vaccination on 4 and 6 Month Old Infants: A Randomized Controlled Clinical Trial Study.International journal of community based nursing and midwifery · 2022Trial
- Effect of combined music and touch intervention on pain response and β-endorphin and cortisol concentrations in late preterm infants.BMC pediatrics · 2017Trial
- Effects of standardized acoustic stimulation in premature infants: a randomized controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2016Trial
- Co-bedding as a Comfort measure For Twins undergoing painful procedures (CComForT Trial).BMC pediatrics · 2009Trial
- Kangaroo Care modifies preterm infant heart rate variability in response to heel stick pain: pilot study.Early human development · 2009Trial
- Nonpharmacological Pain Management for Premature Neonates in Neonatal Intensive Care Units: A Meta-Analysis.Health science reports · 2026Review
- Parent-led neonatal pain management-a narrative review and update of research and practices.Frontiers in pain research (Lausanne, Switzerland) · 2024Review
- Infant pain vs. pain with parental suppression: Immediate and enduring impact on brain, pain and affect.PloS one · 2023Article
- Implementing use of sucrose analgesia (non-pharmacological management of neonatal pain) in a standalone private facility level 3 neonatal care unit using point of care quality improvement methodology.BMJ open quality · 2022Article
- State of the Art in Parent-Delivered Pain-Relieving Interventions in Neonatal Care: A Scoping Review.Frontiers in pediatrics · 2021Article
- Study protocol: parents as pain management in Swedish neonatal care - SWEpap, a multi-center randomized controlled trial.BMC pediatrics · 2020Article
- Neonatal pain: A journey spanning three decades.Paediatric & neonatal pain · 2020Review
- Stress Management among Parents of Neonates Hospitalized in NICU: A Qualitative Study.Journal of caring sciences · 2017Article
- Understanding kangaroo care and its benefits to preterm infants.Pediatric health, medicine and therapeutics · 2015Review
- Anesthesia and analgesia in the NICU.Clinics in perinatology · 2012Review
- Strategies for the prevention and management of neonatal and infant pain.Current pain and headache reports · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo test if enhancing maternal skin-to-skin contact, or kangaroo mother care (KMC) by adding rocking, singing and sucking is more efficacious than simple KMC for procedural pain in preterm neonates. STUDY
designPreterm neonates (n=90) between 32 0/7 and 36 0/7 weeks' gestational age participated in a single-blind randomized crossover design. The infant was held in KMC with the addition of rocking, singing and sucking or the infant was held in KMC without additional stimulation. The Premature Infant Pain Profile was the primary outcome with time to recover as the secondary outcome. A repeated-measures analysis of covariance was employed for analyses.
resultThere were no significant differences in any of the 30 s time periods over the 2 min of blood sampling nor in time to return to baseline. Compared to historical controls of the same age in incubator, the pain scores were lower and comparable to other studies of KMC. There were site differences related to lower scores with the use of sucrose in one site and higher scores in younger, sicker infants in another site.
conclusionThe sensorial stimulations from skin-to-skin contact that include tactile, olfactory sensations from the mother are sufficient to decrease pain response in premature neonates. Other studies showing that rocking, sucking and music were efficacious were independent of skin-to-skin contact, which, when used alone has been shown to be effective as reported across studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.