ArticleVirology2008
Genetic diversity in the yellow head nidovirus complex.
Article in Virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Meta-analysis of public raw sequence data unveils the distribution and dynamics of emerging aquatic pathogens: using Macrobrachium rosenbergii golda virus as a case study.Microbiology spectrum · 2026Pooled it
- Viral Threats to Australian Fish and Prawns: Economic Impacts and Biosecurity Solutions-A Systematic Review.Viruses · 2025Pooled it
- Shrimp Aquaculture Under Viral Threats: Insights into Pathogens and Control Strategies.Food and environmental virology · 2026Review
- History of Shrimp Farming and the Main Viral and Bacterial Diseases in Mexico.Microorganisms · 2025Review
- Review
- Updated roles of the gut microbiota in exploring shrimp etiology, polymicrobial pathogens, and disease incidence.Zoological research · 2024Review
- Failed shrimp vaccination attempt with yellow head virus (YHV) attenuated in an immortal insect cell line.Fish and shellfish immunology reports · 2023Article
- Coinfection with Yellow Head Virus Genotype 8 (YHV-8) and Oriental Wenrivirus 1 (OWV1) in WildViruses · 2023Article
- Classification, replication, and transcription ofFrontiers in microbiology · 2023Review
- Viral Shrimp Diseases Listed by the OIE: A Review.Viruses · 2022Review
- Computational drug repurposing study of the RNA binding domain of SARS-CoV-2 nucleocapsid protein with antiviral agents.Biotechnology progress · 2021Article
- ICTV Virus Taxonomy Profile:The Journal of general virology · 2021Review
- Article
- Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales.Journal of virology · 2016Article
- The effects of Nigella sativa (Ns), Anthemis hyalina (Ah) and Citrus sinensis (Cs) extracts on the replication of coronavirus and the expression of TRP genes family.Molecular biology reports · 2014Article
- Immunological-based assays for specific detection of shrimp viruses.World journal of virology · 2014Review
- Shrimp viral diseases, import risk assessment and international trade.Indian journal of virology : an official organ of Indian Virological Society · 2012Article
- Shrimp molecular responses to viral pathogens.Marine biotechnology (New York, N.Y.) · 2011Review
- RNA-binding domain in the nucleocapsid protein of gill-associated nidovirus of penaeid shrimp.PloS one · 2011Article
- Gene expression kinetics of the yellow head virus in experimentally infectedAquaculture research · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Penaeus monodon shrimp collected from across the Indo-Pacific region during 1997-2004 were screened for the presence of yellow head-related viruses. Phylogenetic analyses of amplified ORF1b gene segments identified at least six distinct genetic lineages (genotypes). Genotype 1 (YHV) was detected only in shrimp with yellow head disease. Genotype 2 (GAV) was detected in diseased shrimp with the less severe condition described as mid-crop mortality syndrome and in healthy shrimp from Australia, Thailand and Vietnam. Other genotypes occurred commonly in healthy shrimp. Sequence comparisons of structural protein genes (ORF2 and ORF3), intergenic regions (IGRs) and the long 3'-UTR supported the delineation of genotypes and identified both conserved and variant structural features. In putative transcription regulating sequences (TRSs) encompassing the sub-genomic mRNA 5'-termini, a core motif (5'-GUCAAUUACAAC-3') is absolutely conserved. A small (83 nt) open reading frame (ORF4) in the 3'-UTR of GAV is variously truncated in all other genotypes and a TRS-like element preceding ORF4 is invariably corrupted by a A>G/U substitution in the central core motif (5'-UU(G/U)CAAC-3'). The data support previous evidence that ORF4 is a non-functional gene under construction or deconstruction. The 3'-UTRs also contain predicted 3'-terminal hairpin-loop structures that are preserved in all genotypes by compensatory nucleotide substitutions, suggesting a role in polymerase recognition for minus-strand RNA synthesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.