Evidence map›Paper›PMID 18767902›Full record

ReviewPLoS medicine2008

Key issues in conducting a meta-analysis of gene expression microarray datasets.

Adaikalavan Ramasamy, Adrian Mondry, Chris C Holmes, Douglas G Altman

Abstract readReview
In one paragraph

Review in PLoS medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 310 papers, 65 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
310citing papers in PubMed, 65 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

310 citing papers in PubMed, 65 syntheses or guidelines pooled it.

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250 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adaikalavan RamasamyCentre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom. ramasamy@stats.ox.ac.uk
Adrian Mondry
Chris C Holmes
Douglas G Altman

Funding

Cancer Research UKMedical Research Council G0500115Medical Research Council MC_UP_A390_1107
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Databases, GeneticMeta-Analysis as TopicAnimalsGene Expression RegulationHumansOligonucleotide Array Sequence Analysis

Identifiers

PMID18767902
PMCPMC2528050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.