Evidence map›Paper›PMID 18765922›Full record

ArticleActa crystallographica. Section F, Structural biology and crystallization communications2008

Crystallization and X-ray analysis of the Schistosoma mansoni guanidino kinase.

Ayman M Awama, Patricia Paracuellos, Sabine Laurent, Colette Dissous, Olivier Marcillat, Patrice Gouet

Abstract readComparative Study
In one paragraph

Article in Acta crystallographica. Section F, Structural biology and crystallization communications, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayman M AwamaInstitut de Chimie et Biochimie Moléculaire et Supramoléculaire, CNRS UMR 5246 et Université de Lyon, F-69622 Villeurbanne, France.
Patricia Paracuellos
Sabine Laurent
Colette Dissous
Olivier Marcillat
Patrice Gouet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 716-amino-acid guanidino kinase from the parasitic flatworm Schistosoma mansoni results from the fusion of two guanidino kinase subunits. Crystals of this 80 kDa protein have been obtained in the monoclinic space group P2(1), with unit-cell parameters a = 52.7, b = 122.1, c = 63.2 A, beta = 108.5 degrees . Synchrotron data were collected to 2.8 A resolution on ESRF beamline ID29. The structure was solved by the molecular-replacement method, using the 357-amino-acid structure of the arginine kinase from Trypanosoma cruzi as the search model.

Indexed as

Amino Acid SequenceAnimalsCrystallizationCrystallography, X-RayGTP PyrophosphokinaseMolecular Sequence DataSchistosoma mansoniGTP Pyrophosphokinase

Identifiers

PMID18765922
PMCPMC2531260

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.