Evidence map›Paper›PMID 18765914›Full record

ArticleActa crystallographica. Section F, Structural biology and crystallization communications2008

Crystallization and preliminary crystallographic analysis of the complex of the second and third regulatory subunits of human Pol delta.

Andrey G Baranovskiy, Nigar D Babayeva, Youri I Pavlov, Tahir H Tahirov

Abstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology and crystallization communications, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrey G BaranovskiyEppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198-7696, USA.
Nigar D Babayeva
Youri I Pavlov
Tahir H Tahirov

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Apar Kishor Ganti · 1985 to 2026
$55.0M
NCI NIH HHS P30 CA036727NCI NIH HHS P30CA036727
6 · The paper itself

Abstract

Human DNA polymerase delta (Pol delta) consists of four subunits: p125, p50, p66 and p12. A heterodimer containing a His-tagged p50 subunit (p50) and a p50-interacting domain of the p66 subunit (p66(N)) was crystallized. The crystal was in the form of a prism with a rhombic cross-section and belonged to space group P2(1). The crystal had unit-cell parameters a = 95.13, b = 248.54, c = 103.46 A, beta = 106.94 degrees and diffracted to a resolution of 3 A. Four molecules of p50-p66(N) in an asymmetric unit corresponded to a crystal solvent content of 72.2%.

Indexed as

Protein Structure, QuaternaryCrystallizationCrystallography, X-RayDimerizationDNA Polymerase IIIHumansProtein SubunitsDNA Polymerase IIIPOLD3 protein, humanProtein Subunits

Identifiers

PMID18765914
PMCPMC2531283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.