Evidence map›Paper›PMID 18765113›Full record

ReviewCurrent urology reports2008

Androgen deprivation therapy and risk for diabetes and cardiovascular disease in prostate cancer survivors.

Matthew R Smith

Registry-linked trialAbstract readReview
In one paragraph

Review in Current urology reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03888742 (A Cross Sectional Study to Assess the Effect of Androgen Deprivation Therapy on Gut and Urinary Microbiota in Patients With Prostate Cancer), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03888742 completednot on this mapstarted 2018, after this paper: background citation

A Cross Sectional Study to Assess the Effect of Androgen Deprivation Therapy on Gut and Urinary Microbiota in Patients With Prostate Cancer

TypeobservationalSponsorChinese University of Hong KongRan2018 to 2021Enrolled214ConditionsProstate Cancer
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Long-term dynamics of bone mineral density during intermittent androgen deprivation for men with nonmetastatic, hormone-sensitive prostate cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012
    Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Androgen receptor (AR) in cardiovascular diseases.The Journal of endocrinology · 2016
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Matthew R SmithMassachusetts General Hospital Cancer Center, Yawkey Center 7038, 55 Fruit Street, Boston, MA 02114, USA. smith.matthew@mgh.harvard.edu
Center for Cancer Research · US

Funding

Midcareer Investigator AwardK24CA121990 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SMITH, MATTHEW RAYMOND · 2007 to 2016
$1.9M
NCI NIH HHS K24 CA121990
6 · The paper itself

Abstract

Gonadotropin-releasing hormone (GnRH) agonists are the mainstay of treatment for recurrent and metastatic prostate cancer. GnRH agonists are also an important part of therapy for many men with localized or locally advanced prostate cancer. Although GnRH agonists improve survival in certain settings, they involve adverse effects including vasomotor flushing, obesity, and osteoporosis. This article describes the evidence that GnRH agonists increase risk for diabetes and cardiovascular disease and reviews the potential mechanisms for treatment-related morbidity.

Indexed as

Cardiovascular DiseasesDiabetes MellitusGonadotropin-Releasing HormoneHumansMaleProstatic NeoplasmsRisk FactorsSurvivorsGonadotropin-Releasing Hormone

Identifiers

PMID18765113
PMCPMC3047401
OpenAlexW2012180347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.