Evidence map›Paper›PMID 18764300›Full record

ArticlePhysical review letters2008

Test of the Gouy-Chapman theory for a charged lipid membrane against explicit-solvent molecular dynamics simulations.

Myunggi Yi, Hugh Nymeyer, Huan-Xiang Zhou

Abstract read
In one paragraph

Article in Physical review letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Concentration dependence of NaCl ion distributions around DPPC lipid bilayers.Interdisciplinary sciences, computational life sciences · 2011
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Myunggi YiDepartment of Physics, Florida State University, Tallahassee, Florida 32306, USA.
Hugh Nymeyer
Huan-Xiang Zhou

Funding

THEORY OF PROTEIN/PROTEIN ASSOCIATIONR01GM058187 · NIGMS · FLORIDA STATE UNIVERSITY · PI ZHOU, HUAN-XIANG · 1998 to 2016
$3.7M
NIGMS NIH HHS GM058187NIGMS NIH HHS R01 GM058187
6 · The paper itself

Abstract

A wealth of experimental data has verified the applicability of the Gouy-Chapman (GC) theory to charged lipid membranes. Surprisingly, a validation of GC by molecular dynamics (MD) simulations has been elusive. Here, we report a test of GC against extensive MD simulations of an anionic lipid bilayer solvated by water at different concentrations of NaCl or KCl. We demonstrate that the ion distributions from the simulations agree remarkably well with GC predictions when information on the adsorption of counterions to the bilayer is incorporated.

Indexed as

Models, ChemicalAlgorithmsComputer SimulationLipid BilayersMembrane LipidsPhosphatidylglycerolsSodium ChlorideStatic ElectricitySurface Properties1,2-dioleoyl-sn-glycero-3-phosphoglycerolLipid BilayersMembrane LipidsPhosphatidylglycerolsSodium Chloride

Identifiers

PMID18764300
PMCPMC3532908

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.