Evidence map›Paper›PMID 18762512›Full record

ReviewPediatrics2008

Retinoblastoma: one world, one vision.

Carlos Rodriguez-Galindo, Mathew W Wilson, Guillermo Chantada, Ligia Fu, Ibrahim Qaddoumi, Célia Antoneli, Carlos Leal-Leal, Tarun Sharma, Margarita Barnoya, Sidnei Epelman and 14 more

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07530458 (Retinoblastoma Consolidation), which is not on this map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07530458 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Retinoblastoma Consolidation: A Retrospective Multivariate Analysis In Egyptian Population

TypeobservationalSponsorAssiut UniversityRan2026 to 2027Enrolled150ConditionsRetinoblastomaArmstranspupillary thermotherapy, Cryotherapy, Brachytherapy
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 139 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Retinoblastoma in Asia.Eye (London, England) · 2019
    Review
  19. Head and Eye Trauma Before Retinoblastoma Diagnosis.Cancer management and research · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 14 institutions in 8 countries.

Carlos Rodriguez-GalindoDepartment of Oncology, St Jude Children's Research Hospital, 332 N Lauderdale, Memphis, TN 38105, USA. carlos.rodriguez-galindo@stjude.org
Mathew W Wilson
Guillermo Chantada
Ligia Fu
Ibrahim Qaddoumi
Célia Antoneli
Carlos Leal-Leal
Tarun Sharma
Margarita Barnoya
Sidnei Epelman
Louis Pizzarello
Javier R Kane
Ray Barfield
Thomas E Merchant
Leslie L Robison
A Linn Murphree
Patricia Chevez-Barrios
Michael A Dyer
Joan O'Brien
Raul C Ribeiro
John Hungerford
Eugene M Helveston
Barrett G Haik
Judith Wilimas
St. Jude Children's Research Hospital · USUniversity of Tennessee Health Science Center · USAC Camargo Hospital · BRBrazilian Network Information Center · BRChildren's Cancer Center · USChildren's Hospital of Los Angeles · USGarrahan Hospital · ARIndiana University School of MedicineInstituto Nacional de Pediatria · MXKing Hussein Cancer Center · JOSankara Nethralaya · INSt Bartholomew's Hospital · GBUniversidad Metropolitana de Honduras · HNUniversity of California, San Francisco · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
XENOGRAFT STUDIESP01CA023099 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HOUGHTON, PETER J · 1985 to 2011
$22.4M
NCI NIH HHS CA 23099NCI NIH HHS P01 CA023099NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

Retinoblastoma is curable when diagnosed early and treated appropriately; however, the prognosis is dismal when the basic elements of diagnosis and treatment are lacking. In developing countries, poor education, lower socioeconomic conditions, and inefficient health care systems result in delayed diagnosis and suboptimal care. Furthermore, the complexity of multidisciplinary care required is seldom possible. Whereas ocular salvage is a priority in the Western world, death from retinoblastoma is still a major problem in developing countries. To bring the 2 ends of this spectrum together and provide a forum for discussion, the "One World, One Vision" symposium was organized, at which clinicians and researchers from various cultural, geographic, and socioeconomic backgrounds converged to discuss their experiences. Strategies for early diagnosis in developing countries were discussed. Elements of the development of retinoblastoma centers in developing countries were discussed, and examples of successful programs were highlighted. An important component in this process is twinning between centers in developing countries and mentor institutions in high-income countries. Global initiatives by nongovernmental organizations such as the International Network for Cancer Treatment and Research, Orbis International, and the International Agency for Prevention of Blindness were presented. Treatment of retinoblastoma in developing countries remains a challenge; however, it is possible to coordinate efforts at multiple levels, including public administrations and nonprofit organizations, to improve the diagnosis and treatment of retinoblastoma and to improve the outcome for these children.

Indexed as

Quality Assurance, Health CareRetinal NeoplasmsRetinoblastomaChildCombined Modality TherapyDeveloping CountriesDiagnosis, DifferentialHumansPrevalencePrognosisRisk FactorsSocioeconomic FactorsSurvival Rate

Identifiers

PMID18762512
PMCPMC2844325
OpenAlexW2010568031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.