Evidence map›Paper›PMID 18761271›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Paucity of anginal symptoms and stress-induced perfusion abnormalities in ischemic cardiomyopathy.

Alessia Gimelli, Paolo Marzullo, Patrizia Landi, Antonio L'Abbate, Matteo Bottai, Daniele Rovai

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Relationship between myocardial perfusion abnormalities and contractile impairment in anginal patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alessia GimelliCNR, Institute of Clinical Physiology, Pisa, Italy.
Paolo Marzullo
Patrizia Landi
Antonio L'Abbate
Matteo Bottai
Daniele Rovai
Istituto di Fisiologia Clinica · ITUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe sought to investigate whether the paucity of anginal symptoms in patients with ischemic cardiomyopathy reflects a reduction in the severity of stress-induced myocardial ischemia. METHODS AND

resultsWe selected 38 patients with coronary artery disease and severe left ventricular dysfunction (ejection fraction [EF] <or=25%) (group 1), who underwent stress gated single photon emission computed tomography. In parallel, we selected 2 groups of 38 patients with coronary artery disease and EF between 26% and 45% (group 2) or EF greater than 45% (group 3), matched to group 1 patients. Effort angina was less frequent in group 1 (29%) than in group 2 (50%) and group 3 (82%) (P = .023). Stress-induced perfusion abnormalities, identified by the summed difference score (SDS), were less extensive in group 1 (mean SDS, 3 +/- 3) than in group 2 (mean SDS, 6 +/- 5) and group 3 (mean SDS, 8 +/- 4) (P = .019), whereas perfusion abnormalities at rest (summed rest score [SRS]) were more extensive in group 1 (mean SRS, 12 +/- 4) than in group 2 (mean SRS, 6 +/- 3) and group 3 (mean SRS, 3 +/- 2) (P = .015).

conclusionThe paucity of anginal symptoms in ischemic cardiomyopathy reflects a limited extent of stress-induced myocardial ischemia and a higher extent of necrosis.

Indexed as

AgedAngina PectorisCardiomyopathiesExercise TestFemaleGated Blood-Pool ImagingHumansMaleMiddle AgedMyocardial IschemiaNecrosisPerfusionProspective StudiesTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, Left

Identifiers

PMID18761271
OpenAlexW2077985351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.