ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Direct imaging of myocardial ischemia: a potential new paradigm in nuclear cardiovascular imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Assessment of acute myocardial infarction: current status and recommendations from the North American society for Cardiovascular Imaging and the European Society of Cardiac Radiology.The international journal of cardiovascular imaging · 2011Guideline
- Value of combined perfusion and metabolic tracers versus stress-rest perfusion imaging for coronary heart disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Reperfusion Microvascular Ischemia After Prolonged Coronary Occlusion: Implications And Treatment With Local Supersaturated Oxygen Delivery.Hypoxia (Auckland, N.Z.) · 2019Article
- Direct myocardial ischemia imaging: a new cardiovascular nuclear imaging paradigm.Clinical cardiology · 2015Review
- Direct myocardial ischemia imaging with exercise ¹⁸FDG.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Tc-99m glucoheptonate is poor man's fluorodeoxyglucose.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India · 2011Article
- Exercise (18)FDG imaging for the detection of CAD: What are the clinical hurdles?Current cardiology reports · 2010Review
- Can we enhance the detection of ischemia and better identify high risk coronary artery disease by imaging of myocardial metabolism?Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyArticle
- Developing a new PET myocardial perfusion tracer.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myocardial perfusion imaging has been in clinical use for over 30 years, serving as an effective, reliable, and relatively simple tool for diagnosis, risk stratification, and long-term follow-up of patients with suspected or known coronary artery disease. However, a unique strength of nuclear imaging is its ability to provide tools for imaging biochemical and metabolic processes and receptor and transporter functions at molecular and cellular levels in intact organisms under a wide variety of physiologic conditions. Despite their high resolution and technical sophistication, other imaging modalities currently do not have this capability. Metabolic imaging techniques using radiolabeled free fatty acid and glucose analogs provide a unique ability to image myocardial ischemia directly in patients with known or suspected coronary artery disease. These techniques can potentially overcome some of the limitations of currently used stress-rest perfusion imaging and also provide a unique opportunity to detect and image an episode of ischemia in the preceding hours even in the absence of other markers of ongoing myocardial ischemia. We describe recent studies using fluorine 18-labeled deoxyglucose and iodine 123 beta-methyl-p-iodophenyl-pentadecanoic acid for imaging myocardial ischemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.