Evidence map›Paper›PMID 18760751›Full record

ArticleHeart failure clinics2008

Epidemiology of chronic kidney disease in heart failure.

Ali Ahmed, Ruth C Campbell

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Heart failure clinics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05719714 (Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease), which is not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05719714 phase1 / phase2active not recruitingstarted 2024, after this paper: background citation

Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease

Ran2024Enrolled18Registered outcomes5Posted comparisons0ConditionsChronic Kidney Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Kidney DiseasesArmsDapagliflozin 10 MG [Farxiga]
Open the trial in the graph
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
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  13. Review
  14. Article
  15. Heart Failure and Osteoporosis: Shared Challenges in the Aging Population.Journal of cardiovascular development and disease · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. A Retrospective Analysis of Sacubitril/Valsartan in Heart Failure and Chronic Kidney Disease.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2023
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ali AhmedUniversity of Alabama at Birmingham, Birmingham, AL 35294-2041, USA. aahmed@uab.edu
Ruth C Campbell

Funding

The Impact on Diabetes on Left Ventricular RemodelingP50HL077100 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHATHAM, JOHN C · 2005 to 2009
$16.5M
Heart failure, chronic kidney disease, and renin-angiotensin system inhibitionR01HL085561 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMED, ALI · 2006 to 2009
$1.5M
Effect:pioglitazone on proteinuria in type 2 diabetesK23DK064649 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CAMPBELL, RUTH CLAIRE · 2005 to 2009
$554k
NHLBI NIH HHS 5-R01-HL085561-02NHLBI NIH HHS P50 HL077100NHLBI NIH HHS P50-HL077100NHLBI NIH HHS R01 HL085561NIDDK NIH HHS 1-K23-DK-64649-1A2NIDDK NIH HHS K23 DK064649
6 · The paper itself

Abstract

Heart failure is common and is associated with a poor prognosis. Chronic kidney disease is common in heart failure and shares many risk factors with heart failure, such as age, hypertension, diabetes, and coronary artery disease. Over half of all patients who have heart failure may have moderate-to-severe chronic kidney disease. The presence of chronic kidney disease is associated with increased morbidity and mortality, yet it is also associated with underuse of evidence-based heart failure therapy that may reduce morbidity and mortality. Understanding the epidemiology and outcomes of chronic kidney disease in heart failure is essential to ensure proper management of these patients.

Indexed as

Aged, 80 and overFemaleGlomerular Filtration RateHeart FailureHumansKidney Failure, ChronicMaleMiddle AgedPrognosisRisk FactorsUnited States

Identifiers

PMID18760751
PMCPMC2900793

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.