ReviewCurrent opinion in biotechnology2008
Life in hot acid: pathway analyses in extremely thermoacidophilic archaea.
Review in Current opinion in biotechnology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Evolutionary cell biology comes of age.Journal of cell science · 2025Article
- Lipid hydrogen isotope compositions primarily reflect growth water in the model archaeonApplied and environmental microbiology · 2025Article
- Article
- Genome-wide transcriptional response to silver stress in extremely halophilic archaeon Haloferax alexandrinus DSM 27206BMC microbiology · 2023Article
- Microbial application in remediation of heavy metals: an overview.Archives of microbiology · 2022Review
- Microbial Community Structure Along a Horizontal Oxygen Gradient in a Costa Rican Volcanic Influenced Acid Rock Drainage System.Microbial ecology · 2020Article
- The Cell Membrane ofInternational journal of molecular sciences · 2020Review
- Thermoplasmatales and sulfur-oxidizing bacteria dominate the microbial community at the surface water of a COExtremophiles : life under extreme conditions · 2019Article
- Structural insights into the inhibition properties of archaeon citrate synthase from Metallosphaera sedula.PloS one · 2019Article
- In a quest for engineering acidophiles for biomining applications: challenges and opportunities.Genes · 2018Review
- An Insight Into Ameliorating Production, Catalytic Efficiency, Thermostability and Starch Saccharification of Acid-Stable α-Amylases From Acidophiles.Frontiers in bioengineering and biotechnology · 2018Review
- VapC toxins drive cellular dormancy under uranium stress for the extreme thermoacidophile Metallosphaera prunae.Environmental microbiology · 2017Article
- Biological Phosphorus Removal During High-Rate, Low-Temperature, Anaerobic Digestion of Wastewater.Frontiers in microbiology · 2016Article
- Identification and characterization of 2-keto-3-deoxy-L-rhamnonate dehydrogenase belonging to the MDR superfamily from the thermoacidophilic bacterium Sulfobacillus thermosulfidooxidans: implications to L-rhamnose metabolism in archaea.Extremophiles : life under extreme conditions · 2015Article
- Biochemical and Structural Properties of a Thermostable Mercuric Ion Reductase from Metallosphaera sedula.Frontiers in bioengineering and biotechnology · 2015Article
- SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase.BMC research notes · 2014Article
- Metal resistance and lithoautotrophy in the extreme thermoacidophile Metallosphaera sedula.Journal of bacteriology · 2012Article
- Inorganic polyphosphates in extremophiles and their possible functions.Extremophiles : life under extreme conditions · 2012Article
- Structural and enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus.PloS one · 2012Article
- A proton shelter inspired by the sugar coating of acidophilic archaea.Scientific reports · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The extremely thermoacidophilic archaea are a particularly intriguing group of microorganisms that must simultaneously cope with biologically extreme pHs (< or = 4) and temperatures (Topt > or = 60 degrees C) in their natural environments. Their expanding biotechnological significance relates to their role in biomining of base and precious metals and their unique mechanisms of survival in hot acid, at both the cellular and biomolecular levels. Recent developments, such as advances in understanding of heavy metal tolerance mechanisms, implementation of a genetic system, and discovery of a new carbon fixation pathway, have been facilitated by the availability of genome sequence data and molecular genetic systems. As a result, new insights into the metabolic pathways and physiological features that define extreme thermoacidophily have been obtained, in some cases suggesting prospects for biotechnological opportunities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.