Evidence map›Paper›PMID 18759491›Full record

ArticleNano letters2008

Water soluble single-walled carbon nanotubes inhibit stimulated endocytosis in neurons.

Erik B Malarkey, Reno C Reyes, Bin Zhao, Robert C Haddon, Vladimir Parpura

Abstract read
In one paragraph

Article in Nano letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Probing astroglia with carbon nanotubes: modulation of form and function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Review
  7. A review of organic and inorganic biomaterials for neural interfaces.Advanced materials (Deerfield Beach, Fla.) · 2014
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erik B MalarkeyDepartment of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F. McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA.
Reno C Reyes
Bin Zhao
Robert C Haddon
Vladimir Parpura

Funding

Calcium-dependent glutamate release from astrocytesR01MH069791 · NIMH · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI PARPURA, VLADIMIR · 2004 to 2008
$1.2M
NIMH NIH HHS R01 MH 069791NIMH NIH HHS R01 MH069791
6 · The paper itself

Abstract

We report the use of chemically functionalized water soluble single-walled carbon nanotube (SWNT) graft copolymers to inhibit endocytosis. The graft copolymers were prepared by the functionalization of SWNTs with polyethylene glycol. When added to the culturing medium, these functionalized water soluble SWNTs were able to increase the length of various neuronal processes, neurites, as previously reported. Here we have determined that SWNTs are able to block stimulated membrane endocytosis in neurons, which could then explain the previously noted extended neurite length.

Indexed as

EndocytosisAnimalsCell MembraneModels, BiologicalNanotechnologyNanotubesNanotubes, CarbonNeuritesNeuronsPhosphopyruvate HydratasePolymersRatsRats, Sprague-DawleyTime FactorsWaterNanotubes, CarbonPhosphopyruvate HydratasePolymersWater

Identifiers

PMID18759491
PMCPMC2637913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.