SynthesisOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2009
Risk factors for low BMD in healthy men age 50 years or older: a systematic review.
Synthesis in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Inequities Across the Spectrum of Osteoporosis Care and Post-Fracture Management in Men.Current osteoporosis reports · 2025Review
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- Policies for healthy ageing in response to climate change: Protocol of a systematic review.PloS one · 2025Article
- Prevalence and Risk Factors of Osteoporosis among Postmenopausal Women Visiting a District Hospital of Nepal: An Observational Study.JNMA; journal of the Nepal Medical Association · 2024Observational
- Association between Bone Quality and Physical Activity in Community-Dwelling Older Adults.Geriatrics (Basel, Switzerland) · 2024Article
- Association of vitamins with bone mineral density and osteoporosis measured by dual-energy x-ray absorptiometry: a cross-sectional study.BMC musculoskeletal disorders · 2024Article
- Association of alcohol and bone mineral density dependent on type of alcohol consumed.Journal of bone and mineral metabolism · 2023Article
- Associations of bone mineral density with sex hormone-binding globulin (SHBG) and testosterone in middle-aged Saudi men: a cross-sectional study.Frontiers in endocrinology · 2023Article
- Article
- The study of bone mineral density measured by quantitative computed tomography in middle-aged and elderly men with abnormal glucose metabolism.BMC endocrine disorders · 2022Article
- Risk Factors Analysis of Bone Mineral Density Based on Lasso and Quantile Regression in America during 2015-2018.International journal of environmental research and public health · 2021Article
- Gender Differences in Osteoporosis: A Single-Center Observational Study.The world journal of men's health · 2021Article
- Associations of Sex Hormone-binding Globulin with Bone Mineral Density Among US Adults, NHANES 2013-2016.International journal of general medicine · 2021Article
- Risk factors and renal outcomes of low bone mineral density in patients with non-dialysis chronic kidney disease.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- Machine Learning Approaches for Fracture Risk Assessment: A Comparative Analysis of Genomic and Phenotypic Data in 5130 Older Men.Calcified tissue international · 2020Article
- Association between liver enzymes and bone mineral density in Koreans: a cross-sectional study.BMC musculoskeletal disorders · 2018Article
- Correlates of Level and Loss of Grip Strength in Later Life: Findings from the English Longitudinal Study of Ageing and the Hertfordshire Cohort Study.Calcified tissue international · 2018Article
- Article
- Active smoking and COPD phenotype: distribution and impact on prognostic factors.International journal of chronic obstructive pulmonary disease · 2017Observational
- Bone microstructure in men assessed by HR-pQCT: Associations with risk factors and differences between men with normal, low, and osteoporosis-range areal BMD.Bone reports · 2016Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
summaryIn this systematic review, we summarize risk factors for low bone mineral density and bone loss in healthy men age 50 years or older. Consistent risk factors were: age, smoking, low weight, physical/functional limitations, and previous fracture. Data specific to men has clinical and policy implications.
introductionOsteoporosis is a significant health care problem in men as well as women, yet the majority of evidence on diagnosis and management of osteoporosis is focused on postmenopausal women. The objective of this systematic review is to examine risk factors for low bone mineral density (BMD) and bone loss in healthy men age 50 years or older. MATERIALS AND
methodsA systematic search for observational studies was conducted in MEDLINE, Cochrane Database of Systematic Reviews, DARE, CENTRAL, CINAHL and Embase, Health STAR. The three main search concepts were bone density, densitometry, and risk factors. Trained reviewers assessed articles using a priori criteria.
resultsOf 642 screened abstracts, 299 articles required a full review, and 25 remained in the final assessment. Consistent risk factors for low BMD/bone loss were: advancing age, smoking, and low weight/weight loss. Although less evidence was available, physical/functional limitations and prevalent fracture (after age 50) were also associated with low BMD/bone loss. The evidence was inconsistent or weak for physical activity, alcohol consumption, calcium intake, muscle strength, family history of fracture/osteoporosis, and height/height loss.
conclusionIn this systematic review, we identified several risk factors for low BMD/bone loss in men that are measurable in primary practice.
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