ArticleGenetics2008
The evolutionary rate of duplicated genes under concerted evolution.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 54 citations in OpenAlex.
- Convergence and conflict among telomere-specialized transposons across 60 million years of Drosophilid evolution.Genome research · 2026Article
- Ectopic Gene Conversion Causing Quantitative Trait Variation.Molecular biology and evolution · 2025Article
- The overlooked evolutionary dynamics of 16S rRNA revises its role as the "gold standard" for bacterial species identification.Scientific reports · 2024Article
- Dynamic Molecular Evolution of Mammalian Homeobox Genes: Duplication, Loss, Divergence and Gene Conversion Sculpt PRD Class Repertoires.Journal of molecular evolution · 2021Article
- Multi-dimensional diffusion process of allele frequencies in population genetics.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2021Review
- Duplication history and molecular evolution of the rbcS multigene family in angiosperms.Journal of experimental botany · 2019Article
- The Role of Gene Conversion between Transposable Elements in Rewiring Regulatory Networks.Genome biology and evolution · 2019Review
- di-Cysteine motifs in the C-terminus of plant HMA4 proteins confer nanomolar affinity for zinc and are essential for HMA4 function in vivo.Journal of experimental botany · 2018Article
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- Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays.eLife · 2018Article
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- Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Y chromosome palindromes and gene conversion.Human genetics · 2017Review
- Multicopy gene family evolution on primate Y chromosomes.BMC genomics · 2016Article
- Long-Lasting Gene Conversion Shapes the Convergent Evolution of the Critical Methanogenesis Genes.G3 (Bethesda, Md.) · 2015Article
- Spider Transcriptomes Identify Ancient Large-Scale Gene Duplication Event Potentially Important in Silk Gland Evolution.Genome biology and evolution · 2015Article
- Spreading good news.eLife · 2015Article
- Article
- Interplay of interlocus gene conversion and crossover in segmental duplications under a neutral scenario.G3 (Bethesda, Md.) · 2014Article
- Impact of recurrent gene duplication on adaptation of plant genomes.BMC plant biology · 2014Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of directional selection on the fixation process of a single mutation that spreads in a multigene family by gene conversion is investigated. A simple two-locus model with two alleles, A and a, is first considered in a random-mating diploid population with size N. There are four haplotypes, AA, Aa, aA, and aa, and selection works on the number of alleles A in a diplod (i = 0, 1, 2, 3, 4). Because gene conversion is allowed between the two loci, when the mutation rate is very low, either AA or aa will fix in the population eventually. We consider a situation where a single mutant, A, arises in one locus when a is fixed in both loci. Then, we derive the fixation probability analytically, and the fixation time is investigated by simulations. It is found that gene conversion has an effect to increase the "effective" population size, so that weak selection works more efficiently in a multigene family. With these results, we discuss the effect of gene conversion on the rate of molecular evolution in a multigene family undergoing concerted evolution. We also argue about the applicability of the theoretical results to models of multigene families with more than two loci.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.