ArticleGenetics2008
Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- Article
- Article
- Meiotic sister chromatid exchanges are rare in C. elegans.Current biology : CB · 2021Article
- Meiotic DNA break repair can utilize homolog-independent chromatid templates in C. elegans.Current biology : CB · 2021Article
- Episodes of Rapid Recovery of the Functional Activity of theFrontiers in genetics · 2021Article
- Crossover Position Drives Chromosome Remodeling for Accurate Meiotic Chromosome Segregation.Current biology : CB · 2020Article
- Visualization and Quantification of Transposon Activity inG3 (Bethesda, Md.) · 2019Article
- TheGenetics · 2019Review
- Reprogramming of CaCo2 colorectal cancer cells after using the complex of poly-(N-vinylpyrrolidone) with small non-coding RNAs.Toxicology reports · 2019Article
- Meiosis.WormBook : the online review of C. elegans biology · 2017Review
- Targeted genome engineering inCell & bioscience · 2016Review
- Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis.Nature communications · 2015Article
- Expanding the C. elegans toolbox into a toolshed.Methods (San Diego, Calif.) · 2014Article
- Targeted heritable mutation and gene conversion by Cas9-CRISPR in Caenorhabditis elegans.Genetics · 2013Article
- Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination.Nature methods · 2013Article
- Untangling the web: the diverse functions of the PIWI/piRNA pathway.Molecular reproduction and development · 2013Review
- Article
- Molecular hyperdiversity and evolution in very large populations.Molecular ecology · 2013Article
- COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining.PLoS genetics · 2013Article
- Transposon Invasion of the Paramecium Germline Genome Countered by a Domesticated PiggyBac Transposase and the NHEJ Pathway.International journal of evolutionary biology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Excision of a Mos1 transposon in the germline of Caenorhabditis elegans generates a double-strand break in the chromosome. We demonstrate that breaks are most prominently repaired by gene conversion from the homolog, but also rarely by nonhomologous end-joining. In some cases, gene conversion events are resolved by crossing over. Surprisingly, expression of the transposase using an intestine-specific promoter can induce repair, raising the possibility that activation of transposase expression in somatic cells can lead to transposition of Mos1 in the germline.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.