ReviewCirculation research2008
Chemokines and transplant vasculopathy.
Review in Circulation research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Autologous and synthetic vascular grafts trigger different host responses in the anastomotic regions and in the perivascular adipose tissue during the early healing phase.Materials today. Bio · 2025Article
- Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function.Science translational medicine · 2023Article
- Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways.Frontiers in immunology · 2020Article
- Small Molecule Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Cardiac Allograft Vasculopathy in Murine Aortic Allografts.Transplantation direct · 2018Article
- Encouraging experience using multi-transgenic xenografts in a pig-to-baboon cardiac xenotransplantation model.Xenotransplantation · 2017Article
- Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells.Scientific reports · 2017Article
- Circulating chemokine ligand levels before and after successful kidney transplantation.Journal of inflammation (London, England) · 2016Article
- Risk factors of cardiac allograft vasculopathy.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2015Article
- Transplantation and inflammation: implications for the modification of chemokine function.Immunology · 2014Review
- Effector mechanisms of rejection.Cold Spring Harbor perspectives in medicine · 2013Review
- Production and assessment of decellularized pig and human lung scaffolds.Tissue engineering. Part A · 2013Article
- Chemokines in chronic liver allograft dysfunction pathogenesis and potential therapeutic targets.Clinical & developmental immunology · 2013Review
- A20-mediated modulation of inflammatory and immune responses in aortic allografts and development of transplant arteriosclerosis.Transplantation · 2012Article
- Allograft coronary artery thrombosis: a case report of early cardiac allograft left ventricular myocardial infarction.Methodist DeBakey cardiovascular journal · 2012Article
- The cyclophilin-binding agent Sanglifehrin A is a dendritic cell chemokine and migration inhibitor.PloS one · 2011Article
- Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ mediates pioglitazone-reduced vascular lesion formation.Arteriosclerosis, thrombosis, and vascular biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Transplant vasculopathy (TV) remains the leading cause of late death among heart transplant recipients. Transplant vasculopathy is characterized by progressive neointimal proliferation, leading to ischemic failure of the allograft. Multiple experimental and clinical studies have shown that injury to the graft at various stages of transplantation can be a risk factor for development of transplant vasculopathy. The hallmark of cardiac allograft injury is the infiltration of leukocytes. Recruitment of leukocytes requires intercellular communication between infiltrating cells, endothelium, parenchymal cells, and components of extracellular matrix. These events are mediated via the generation of adhesion molecules, cytokines, and chemokines. The chemokines, by virtue of their specific cell receptor expression, can selectively mediate the local recruitment/activation of distinct leukocytes/cells, allowing for migration across the endothelium and beyond the vascular compartment. This report provides a comprehensive review of the chemokines that participate in the development of transplant vasculopathy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.