Evidence map›Paper›PMID 18757569›Full record

ArticleApplied and environmental microbiology2008

ShmR is essential for utilization of heme as a nutritional iron source in Sinorhizobium meliloti.

Vanesa Amarelle, Mark R O'Brian, Elena Fabiano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Functional Characterization of the CoApplied and environmental microbiology · 2023
    Article
  3. Frontiers in microbiology · 2018
    Article
  4. Iron homeostasis in theAdvances in botanical research · 2013
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Vanesa AmarelleLaboratorio de Ecología Microbiana, Instituto de Investigaciones Biológicas Clemente Estable, MEC, Unidad Asociada a la Facultad de Ciencias, Montevideo 11600, Uruguay.
Mark R O'Brian
Elena Fabiano
Instituto de Investigaciones Biológicas Clemente Estable · UYUniversity at Buffalo, State University of New York · US

Funding

Regulation of Bacterial Heme MetabolismR01GM067966 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI O'BRIAN, MARK R · 2004 to 2012
$2.2M
Heme as an iron source in Sinorhizobium melilotiR03TW007353 · FIC · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI O'BRIAN, MARK R · 2006 to 2008
$114k
FIC NIH HHS R03 TW007353NIGMS NIH HHS GM067966NIGMS NIH HHS R01 GM067966
6 · The paper itself

Abstract

The bacterium Sinorhizobium meliloti is able to use heme as a nutritional iron source. Here, we show that the iron-regulated shmR gene encodes an outer membrane protein required for growth on heme. Furthermore, an shmR mutant is resistant to the toxic heme analog gallium protoporphyrin. Thus, the receptor protein of the heme transport system has been identified in S. meliloti.

Indexed as

Bacterial Outer Membrane ProteinsDrug Resistance, BacterialHemeIronMembrane Transport ProteinsMutationProtoporphyrinsSinorhizobium melilotiBacterial Outer Membrane ProteinsHemeIronMembrane Transport ProteinsProtoporphyrins

Identifiers

PMID18757569
PMCPMC2570276
OpenAlexW2067583008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.