ArticleWorld journal of gastroenterology2008
OCTN and CARD15 gene polymorphism in Chinese patients with inflammatory bowel disease.
Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases.Oncotarget · 2016Pooled it
- Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis.International journal of colorectal disease · 2012Pooled it
- Contribution of the IBD5 locus to inflammatory bowel disease: a meta-analysis.Human genetics · 2011Pooled it
- Review
- Current status of IBD and surgery of Crohn's disease in Thailand.Annals of gastroenterological surgery · 2021Review
- Corticosteroid Treatment at Diagnosis: An Analysis of Relapses, Disease Extension, and Colectomy Rate in Ulcerative Colitis.Digestive diseases and sciences · 2020Article
- Review
- Growth failure in pediatric onset inflammatory bowel disease: mechanisms, epidemiology, and management.Translational pediatrics · 2019Review
- A novel susceptibility locus in MST1 and gene-gene interaction network for Crohn's disease in the Chinese population.Journal of cellular and molecular medicine · 2018Article
- A Systematic Review of Epidemiology and Risk Factors Associated With Chinese Inflammatory Bowel Disease.Frontiers in medicine · 2018Article
- Management of Crohn's disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease.Intestinal research · 2017Review
- Association study betweenThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2017Article
- Family history and disease outcomes in patients with Crohn's disease: A comparison between China and the United States.World journal of gastrointestinal pharmacology and therapeutics · 2016Article
- Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population.Scientific reports · 2016Article
- Corticosteroid therapy in ulcerative colitis: Clinical response and predictors.World journal of gastroenterology · 2015Observational
- CARD15 Gene Polymorphisms Are Associated with Tuberculosis Susceptibility in Chinese Holstein Cows.PloS one · 2015Article
- Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature.World journal of gastrointestinal pathophysiology · 2014Review
- Association of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population.World journal of gastroenterology · 2014Article
- Prediction of Crohn's disease aggression through NOD2/CARD15 gene sequencing in an Australian cohort.World journal of gastroenterology · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the single nucleotide polymorphism (SNPs) distribution of NOD2/CARD15 (R702W, G908R), OCTN1 1672C/T and OCTN2-207G/C in Chinese patients with inflammatory bowel disease (IBD).
methodsA total of 61 patients with Crohn's disease (CD), 151 patients with ulcerative colitis (UC), and 200 unrelated healthy controls were genotyped. Genotyping was performed by sequence specific primer polymerase chain reaction (PCR-SSP) or by restriction fragment length polymorphism (PCR-RFLP) analysis.
resultsAmong the subjects in our study groups, including patients with CD, UC and healthy controls, none had OCTN and CARD15 variants and very rare IBD family history was found in our patients with the percentage of 0 (0/61 with CD) and 1.3% (2/151 with UC).
conclusionOur results indicate that although OCTN or CARD15 variation is associated with susceptibility to IBD in Western populations, these might be rare and may not be associated with susceptibility to IBD in Chinese patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.