Evidence map›Paper›PMID 18756291›Full record

ReviewKidney international2008

Endothelin ETB receptor heterodimerization: beyond the ETA receptor.

Erika I Boesen

Open access · bronzeAbstract readCommentReview
PubMed Publisher
In one paragraph

Review in Kidney international, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Growth Factors in the Carotid Body-An Update.International journal of molecular sciences · 2020
    Review
  2. Article
  3. Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017
    Article
  4. Article
  5. Review
  6. Review
  7. Physiology of endothelin and the kidney.Comprehensive Physiology · 2011
    Review
  8. O-GlcNAcylation: a novel pathway contributing to the effects of endothelin in the vasculature.American journal of physiology. Regulatory, integrative and comparative physiology · 2011
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Erika I Boesen1Vascular Biology Center, Medical College of Georgia, Augusta, Georgia, USA.
Augusta University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The idea that endothelin ETA and ETB receptors may form homodimers and heterodimers has gained increasing interest in recent years. The existence of such interactions between endothelin receptors has the potential to explain some puzzling results from receptor binding and functional studies. Zeng and colleagues take ETB receptor heterodimerization beyond the ETA receptor, reporting renal endothelin ETB-dopamine D(3) receptor interactions at the cellular level that appear to have functional consequences in vivo.

Indexed as

Endothelin-3HumansProtein BindingReceptor, Endothelin AReceptor, Endothelin BReceptors, Dopamine D3Endothelin-3Receptor, Endothelin AReceptor, Endothelin BReceptors, Dopamine D3

Identifiers

PMID18756291
OpenAlexW2015687044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.