Severe pulmonary arterial hypertension: a forme fruste of cancer?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

7 citing papers in PubMed.

1. Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension.The European respiratory journal · 2022
   Article
2. CDC2 Is an Important Driver of Vascular Smooth Muscle Cell Proliferation via FOXM1 and PLK1 in Pulmonary Arterial Hypertension.International journal of molecular sciences · 2021
   Article
3. Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension.PloS one · 2019
   Article
4. Waiting in anticipation: the genetics of pulmonary arterial hypertension.American journal of respiratory and critical care medicine · 2012
   Article
5. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension.American journal of respiratory and critical care medicine · 2010
   Article
6. A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.Clinical pharmacology and therapeutics · 2010
   Article
7. Genomic stability of pulmonary artery endothelial colony-forming cells in culture.Pulmonary circulation
   Article

Corrections and comments

• Comment on
  The cancer paradigm of severe pulmonary arterial hypertension.2008

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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