Evidence map›Paper›PMID 1875451›Full record

ArticleJournal of Tongji Medical University = Tong ji yi ke da xue xue bao1991

Relationship of VLDL receptor and LPL in metabolism of VLDL by macrophage.

Y Z Deng, Z C Feng, H X Wang, W G Jiang, Y Q Zhong, C F Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lipoprotein receptor activity of peritoneal macrophages from insulin-deficient mice.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao · 1991
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Y Z DengDepartment of Biochemistry, Tongji Medical University, Wuhan.
Z C Feng
H X Wang
W G Jiang
Y Q Zhong
C F Wang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages were incubated with 125I-VLDL for 5 h in presence or absence of lipoprotein lipase (LPL) inhibitor, benzene boronic acid (BBA). Both the uptake and degradation of 125I-VLDL by macrophages were saturable, and the uptake and degradation curves were virtually identical. When macrophages were incubated with 125I-VLDL for 10 h in presence of BBA, the uptake and degradation of 125I-VLDL were still saturable. However, in absence of BBA, the uptake and degradation were no longer saturable. The results suggest that with macrophages incubated with VLDL for a shorter period, VLDL was taken up predominantly via receptor pathway, with a longer period of incubation, LPL played a striking role in uptake of VLDL.

Indexed as

AnimalsBoronic AcidsCells, CulturedFemaleLipoprotein LipaseLipoproteins, VLDLMacrophagesMiceReceptors, LDLSwinebenzeneboronic acidBoronic AcidsLipoprotein LipaseLipoproteins, VLDLReceptors, LDLVLDL receptor

Identifiers

PMID1875451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.