ArticlePlant physiology2008
Genetic variation for lettuce seed thermoinhibition is associated with temperature-sensitive expression of abscisic Acid, gibberellin, and ethylene biosynthesis, metabolism, and response genes.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 170 citations in OpenAlex.
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- The initiation of embryo growth in imbibed celery mericarps marks a key mechanism by which temperature signals are integrated to regulate germination timing.Journal of experimental botany · 2026Article
- Molecular mechanisms and breeding strategies for heat tolerance in vegetable crops under global warming.Horticulture research · 2026Article
- Genome-wide association studies in lettuce reveal the interplay of seed age, color, and germination under high temperatures.Scientific reports · 2025Article
- Allelic variation of TaABI5-A4 significantly affects seed dormancy in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Advance in the Thermoinhibition of Lettuce (Plants (Basel, Switzerland) · 2024Review
- The MKK3 MAPK cascade integrates temperature and after-ripening signals to modulate seed germination.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Computing the effects of temperature and osmotic stress on the seed germination of Helianthus annuus L. by using a mathematical model.Scientific reports · 2024Article
- Chemical disruption of ABA signaling overcomes high-temperature inhibition of seed germination and enhances seed priming responses.PloS one · 2024Article
- Genetic, Epigenetic, and Environmental Control of Seed Dormancy and Germination.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Promoter-pervasive transcription causes RNA polymerase II pausing to boost DOG1 expression in response to salt.The EMBO journal · 2023Article
- Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis.Frontiers in plant science · 2023Article
- Cold-induced secondary dormancy and its regulatory mechanisms in Beta vulgaris.Plant, cell & environment · 2022Article
- Enhancement in Seed Priming-Induced Starch Degradation of Rice Seed Under Chilling Stress via GA-Mediated α-Amylase Expression.Rice (New York, N.Y.) · 2022Article
- Article
- The genetic basis of water-use efficiency and yield in lettuce.BMC plant biology · 2021Article
- ABA Metabolism and Homeostasis in Seed Dormancy and Germination.International journal of molecular sciences · 2021Review
- Divergent Selection for Seed Ability to Germinate at Extreme Temperatures in Perennial Ryegrass (Frontiers in plant science · 2021Article
- Morpho-Physiological Traits and Functional Markers Based Molecular Dissection of Heat-Tolerance in Urdbean.Frontiers in plant science · 2021Article
- Toward the Design of Potato Tolerant to Abiotic Stress.Methods in molecular biology (Clifton, N.J.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lettuce (Lactuca sativa 'Salinas') seeds fail to germinate when imbibed at temperatures above 25 degrees C to 30 degrees C (termed thermoinhibition). However, seeds of an accession of Lactuca serriola (UC96US23) do not exhibit thermoinhibition up to 37 degrees C in the light. Comparative genetics, physiology, and gene expression were analyzed in these genotypes to determine the mechanisms governing the regulation of seed germination by temperature. Germination of the two genotypes was differentially sensitive to abscisic acid (ABA) and gibberellin (GA) at elevated temperatures. Quantitative trait loci associated with these phenotypes colocated with a major quantitative trait locus (Htg6.1) from UC96US23 conferring germination thermotolerance. ABA contents were elevated in Salinas seeds that exhibited thermoinhibition, consistent with the ability of fluridone (an ABA biosynthesis inhibitor) to improve germination at high temperatures. Expression of many genes involved in ABA, GA, and ethylene biosynthesis, metabolism, and response was differentially affected by high temperature and light in the two genotypes. In general, ABA-related genes were more highly expressed when germination was inhibited, and GA- and ethylene-related genes were more highly expressed when germination was permitted. In particular, LsNCED4, a gene encoding an enzyme in the ABA biosynthetic pathway, was up-regulated by high temperature only in Salinas seeds and also colocated with Htg6.1. The temperature sensitivity of expression of LsNCED4 may determine the upper temperature limit for lettuce seed germination and may indirectly influence other regulatory pathways via interconnected effects of increased ABA biosynthesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.