Evidence map›Paper›PMID 18752343›Full record

ArticlePLoS medicine2008

Mendelian randomisation and causal inference in observational epidemiology.

Nuala A Sheehan, Vanessa Didelez, Paul R Burton, Martin D Tobin

Abstract read
In one paragraph

Article in PLoS medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 213 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 19 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 19 syntheses or guidelines pooled it.

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  8. High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.Investigative ophthalmology & visual science · 2022
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  20. Trial

153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nuala A SheehanDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom. nas11@le.ac.uk
Vanessa Didelez
Paul R Burton
Martin D Tobin

Funding

Medical Research Council G0501942Medical Research Council G0601625Medical Research Council G9806740
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EpidemiologyObservationRandomized Controlled Trials as TopicHumans

Identifiers

PMID18752343
PMCPMC2522255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.