ArticleHepatology (Baltimore, Md.)2008
Innate immunity and acetaminophen-induced liver injury: why so many controversies?
Article in Hepatology (Baltimore, Md.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Absence of IκBβ/NFκB signaling does not attenuate acetaminophen-induced hepatic injury.Anatomical record (Hoboken, N.J. : 2007) · 2025Article
- Chitinase 3-like protein 1 deficiency ameliorates drug-induced acute liver injury by inhibition of neutrophil recruitment through lipocalin-2.Frontiers in pharmacology · 2025Article
- Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice.Archives of toxicology · 2023Article
- Article
- A history of the roles of cytochrome P450 enzymes in the toxicity of drugs.Toxicological research · 2021Review
- Dissecting the molecular pathophysiology of drug-induced liver injury.World journal of gastroenterology · 2018Review
- Article
- Mechanistic Modelling of Drug-Induced Liver Injury: Investigating the Role of Innate Immune Responses.Gene regulation and systems biology · 2017Article
- A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity.Clinical and translational gastroenterology · 2016Article
- Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.Cell death & disease · 2015Article
- Xenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the Liver.Advances in pharmacology (San Diego, Calif.) · 2015Review
- M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.Free radical biology & medicine · 2015Article
- Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans.Toxicology and applied pharmacology · 2014Article
- Protective effect of Baccharis trimera extract on acute hepatic injury in a model of inflammation induced by acetaminophen.Mediators of inflammation · 2014Article
- Helicobacter hepaticus induces an inflammatory response in primary human hepatocytes.PloS one · 2014Article
- Acetaminophen-induced acute liver injury in HCV transgenic mice.Toxicology and applied pharmacology · 2013Article
- Complement activation in acetaminophen-induced liver injury in mice.The Journal of pharmacology and experimental therapeutics · 2012Article
- Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity.Liver international : official journal of the International Association for the Study of the Liver · 2012Review
- The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity.The Journal of pharmacology and experimental therapeutics · 2011Article
- Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products.Life sciences · 2011Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
18752320What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.